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Table 3 Domain enrichment in proteins under positive selection

From: Pangenome-wide and molecular evolution analyses of the Pseudomonas aeruginosa species

SMART/Pfam domain

Description

Fisher’s test

Chromate_transp

Probably act as chromate transporters in bacteria

0.0000

Sulfatase

Present in esterases hydrolysing steroids, carbohydrates and proteins

0.0020

PepSY_TM

Conserved transmembrane helix found in bacterial protein families

0.0041

PrmA

Present in the Ribosomal protein L11 methyltransferase

0.0123

Cons_hypoth95

Present in 16S RNA methyltransferase D

0.0166

MTS

Present in the 16S RNA methyltransferase C

0.0182

DUF1329

Putative outer membrane lipoprotein

0.0215

DUF4102

Putative phage integrase

0.0235

CHASE

Extracellular domain of bacterial transmembrane receptors

0.0284

G3P_acyltransf

Enzymes converting glycerol-3-phosphate into lysophosphatidic acid

0.0284

AceK

Bacterial isocitrate dehydrogenase kinase/phosphatase protein

0.0284

Choline_sulf_C

C-terminus of enzyme producing choline from choline-O-sulfate

0.0284

DUF2165

Unknown function

0.0284

DUF2909

Unknown function

0.0284

DUF3079

Unknown function

0.0284

DUF444

Unknown function

0.0284

DUF533

Unknown function; integral membrane protein

0.0284

DUF791

Unknown function

0.0284

DUF972

Unknown function

0.0284

Glu_cys_ligase

Enzyme carrying out the first step of glutathione biosynthesis

0.0284

Herpes_UL6

Present in proteins similar to herpes simplex UL6 virion protein

0.0284

His_kinase

Membrane sensor, a two-component regulatory system

0.0284

Inhibitor_I42

Protease inhibitor

0.0284

PPDK_N

Present in enzymes catalysing the conversion of pyrophosphate to PEP

0.0284

Sigma54_AID

Activating interacting domain of the Sigma-54 factor

0.0284

Sigma54_CBD

Core binding domains of the Sigma-54 factor

0.0284

Sigma54_DBD

DNA binding domain of the Sigma-54 factor

0.0284

PAS, PAS 4/9

Present in signalling proteins working as signal sensors

0.0330

MFS

Major Facilitator Superfamily of small molecule transporters

0.0359

Autoind_synth

Autoinducer synthase involved in quorum-sensing response

0.0423

AzIC

Putative protein involved in branched-chain amino acid transport

0.0423

Chitin_bind

Present in carbohydrate-active enzymes (glycoside hydrolases)

0.0423

DUF3299

Unknown function

0.0423

PTS_EIIC / IIB

Phosphoenolpyruvate-dependent phosphotransferase system

0.0423

TctC

Member of the tripartite tricarboxylate receptors

0.0423

UPF0004

Domain found in tRNA methythiotransferases

0.0423

  1. The SMART and Pfam domains are presented in a non-redundant manner. Function description was recovered from annotations in SMART or Pfam databases. Fisher’s test values correspond to p-values (p ≤ 0.05), supporting the over-representation of the corresponding domain in the set of proteins under positive selection