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Table 3 Genes shared between 3 weeks diapause and aging in Drosophila

From: Slowed aging during reproductive dormancy is reflected in genome-wide transcriptome changes in Drosophila melanogaster

Symbol Gene name 3wD (logFC) Longevity effect
ry rosy 2.4 pro
Nlaz Neural Lazarillo 2.38 pro
to takeout 2.21 pro
Zw Zwischenferment 2.18 pro
elav embryonic lethal abnormal vision 1.83 pro
bsk basket 1.69 pro
GstS1 Glutathione S transferase S1 1.68 pro
Nf1 Neurofibromin 1 1.63 pro
CG1623 hebe 1.54 pro
Mlp84B Muscle LIM protein at 84B 1.45 pro
CG11546 kermit 1.43 pro
CG8846 Thor 1.3 pro
Ilp6 Insulin-like peptide 6 1.17 pro
cher cheerio 1.13 pro
rut rutabaga 1.01 pro
srl spargel −1.06 pro
bam bag of marbles −1.18 pro
Daxx Daxx-like protein −1.4 pro
POSH Plenty of SH3s −1.42 pro
CG5671 Pten −1.71 pro
Mt2 Methyltransferase 2 −2.14 pro
Hsp26 Heat shock protein 26 −2.89 pro
Hsp27 Heat shock protein 27 −3.15 pro
CG6284 Sirt6 −3.41 pro
a-Man-Ia alpha Mannosidase I 2.01 anti
Ilp2 Insulin-like peptide 2 1.9 anti
E(z) Enhancer of zeste −1 anti
snz snazarus −1.2 anti
Edem1 ER degradation enhancer mannosidase alpha-like 1 −1.35 anti
kuk kugelkern −1.36 anti
LBR Lamin B receptor −1.91 anti
CG6824 ovo −1.98 anti
esc extra sexcombs −2.44 anti
Hsp22 Hsp22 −1.13 both
  1. Notes: During diapause 34 genes out of 136 hits for aging genes in GenAge database were found to be significantly regulated (q < 0.05, |logFC| > 1). Comparison with the GenAge database [133, 134] http://genomics.senescence.info/genes/