Fig. 4

GO biological processes enriched in genes differentially expressed in in vivo vs. serum. Enriched GO biological processes with Benjamini-Hochberg corrected p-value <0.01, genes per term/pathway ≥5, Goterm levels 3–8, in the genes differentially expressed (FDR corrected p-value <0.05,│FC│ ≥2) in, (a) all the embryos, (b) only male embryos and, (c) only female embryos. The analysis was performed with the ClueGO 2.1.3 plugin of the Cytoscape 3.1.1. The size of the nodules represents their significance; orange nodules are only composed of genes up-regulated in vivo, grey nodules are composed of at least 5 genes up- and 5 genes down-regulated in vivo