Suboptimal culture conditions induce more deviations in gene expression in male than female bovine blastocysts

BMC Genomics

Table 2 Differentially expressed up- and down-regulated genes among the groups compared

Comparison		\|FC\| ≥ 0	\|FC\| ≥ 2	\|FC\| ≥ 5	\|FC\| ≥ 10	\|FC\| ≥ 20	\|FC\| ≥ 50	\|FC\| ≥ 100
All in vivo vs. all serum-containing generated	Total	2186	1109	148	51	24	8	5
	Up	1080	624	78	22	5	1	1
	Down	1106	485	70	29	19	7	4
All in vivo vs. all serum-free generated	Total	534	207	18	3	1	0	0
	Up	223	55	1	0	0	0	0
	Down	311	152	17	3	1	0	0
Male in vivo vs. male serum-containing generated	Total	1801	1283	329	136	68	25	11
	Up	919	760	236	91	46	15	6
	Down	882	523	93	45	22	10	5
Male in vivo vs. male serum-free generated	Total	311	191	28	6	1	1	1
	Up	124	59	4	1	0	0	0
	Down	187	132	24	5	1	1	1
Female in vivo vs. female serum-containing generated	Total	458	456	203	85	41	14	7
	Up	231	229	85	24	9	2	1
	Down	227	227	118	61	32	12	6
Female in vivo vs. female serum-free generated	Total	221	192	77	27	11	2	1
	Up	80	65	21	5	3	0	0
	Down	141	127	56	22	8	2	1
Male in vivo vs. female in vivo generated	Total	225	119	25	18	13	12	11
	Up	69	40	17	14	11	11	11
	Down	156	79	8	4	2	1	0
Male serum-containing vs. female serum containing generated	Total	54	54	47	35	29	17	14
	Up	17	17	15	14	12	11	11
	Down	37	37	32	21	16	6	3
Male serum-free vs. female serum-free generated	Total	54	48	19	13	9	8	8
	Up	14	14	12	10	8	8	8
	Down	40	34	7	3	1	0	0

Number of differentially expressed genes and number of up- or down regulated genes in Group 1 vs. Group 2, with an FDR corrected p-value of <0.05 and an absolute fold change (│FC│) ranging from ≥0 to ≥100

ISSN: 1471-2164