Table 2 GO terms overrepresented among differentially expressed genes
ID | Domain | Term | Annotateda | Significantb | Expectedc | p-value |
|---|---|---|---|---|---|---|
GO terms overrepresented among DEGs with higher expression in the low RFI group than in the high RFI group | ||||||
GO:0044283 | BP | Small molecule biosynthetic process | 170 | 33 | 13.77 | 1.70E-06 |
GO:0046394 | BP | Carboxylic acid biosynthetic process | 113 | 22 | 9.15 | 8.70E-05 |
GO:0016053 | BP | Organic acid biosynthetic process | 113 | 22 | 9.15 | 8.70E-05 |
GO:0006694 | BP | Steroid biosynthetic process | 44 | 12 | 3.56 | 0.00014 |
GO:0046165 | BP | Alcohol biosynthetic process | 48 | 12 | 3.89 | 0.00033 |
GO:0002474 | BP | Antigen processing and presentation of peptide antigen via MHC class I | 20 | 7 | 1.62 | 0.00067 |
GO:1901617 | BP | Organic hydroxy compound biosynthetic process | 60 | 13 | 4.86 | 0.00084 |
GO:0004298 | MF | Threonine-type endopeptidase activity | 15 | 9 | 1.18 | 3.50E-07 |
GO:0005839 | CC | Proteasome core complex | 15 | 9 | 1.23 | 5.10E-07 |
GO:0000502 | CC | Proteasome complex | 39 | 14 | 3.2 | 1.20E-06 |
GO:0005739 | CC | Mitochondrion | 955 | 116 | 78.35 | 4.60E-06 |
GO:0005689 | CC | U12-type spliceosomal complex | 17 | 8 | 1.39 | 2.50E-05 |
GO:0043227 | CC | Membrane-bounded organelle | 5518 | 491 | 452.73 | 0.00039 |
GO:0032991 | CC | Macromolecular complex | 2416 | 237 | 198.23 | 0.00041 |
GO terms overrepresented among DEGs with lower expression in the low RFI group than in the high RFI group | ||||||
GO:0065007 | BP | Biological regulation | 4577 | 285 | 237.14 | 1.10E-06 |
GO:0050789 | BP | Regulation of biological process | 4395 | 272 | 227.71 | 7.00E-06 |
GO:0007165 | BP | Signal transduction | 2117 | 149 | 109.68 | 9.70E-06 |
GO:0030282 | BP | Bone mineralization | 45 | 11 | 2.33 | 1.30E-05 |
GO:0023052 | BP | Signaling | 2276 | 156 | 117.92 | 2.50E-05 |
GO:0044700 | BP | Single organism signaling | 2276 | 156 | 117.92 | 2.50E-05 |
GO:0007166 | BP | Cell surface receptor signaling pathway | 979 | 79 | 50.72 | 2.90E-05 |
GO:0031214 | BP | Biomineral tissue development | 49 | 11 | 2.54 | 3.10E-05 |
GO:0050794 | BP | Regulation of cellular process | 4126 | 254 | 213.77 | 4.40E-05 |
GO:0007154 | BP | Cell communication | 2328 | 157 | 120.61 | 5.70E-05 |
GO:0042325 | BP | Regulation of phosphorylation | 525 | 48 | 27.2 | 7.10E-05 |
GO:0016310 | BP | Phosphorylation | 1024 | 80 | 53.05 | 8.10E-05 |
GO:0044763 | BP | Single-organism cellular process | 5419 | 315 | 280.76 | 0.00021 |
GO:0018212 | BP | Peptidyl-tyrosine modification | 125 | 17 | 6.48 | 0.00023 |
GO:0001932 | BP | Regulation of protein phosphorylation | 407 | 38 | 21.09 | 0.00027 |
GO:0006468 | BP | Protein phosphorylation | 774 | 62 | 40.1 | 0.0003 |
GO:0051716 | BP | Cellular response to stimulus | 2670 | 171 | 138.33 | 0.00041 |
GO:0060070 | BP | Canonical Wnt signaling pathway | 86 | 13 | 4.46 | 0.00044 |
GO:0016477 | BP | Cell migration | 405 | 37 | 20.98 | 0.0005 |
GO:0051239 | BP | Regulation of multicellular organismal process | 841 | 65 | 43.57 | 0.00056 |
GO:0018108 | BP | Peptidyl-tyrosine phosphorylation | 123 | 16 | 6.37 | 0.00058 |
GO:2000026 | BP | Regulation of multicellular organismal development | 526 | 44 | 27.25 | 0.00099 |
GO:0040011 | BP | Locomotion | 511 | 43 | 26.48 | 0.00101 |
GO:0060089 | MF | Molecular transducer activity | 409 | 41 | 21.42 | 4.30E-05 |
GO:0044459 | CC | Plasma membrane part | 537 | 45 | 27.48 | 0.00063 |