|
1,4-dimethoxybenzene (DMB)
|
Ingredient in consumer products
|
---
|
---
|
|
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
|
Industrial byproduct
|
aromatic hydrocarbon (Ah) receptor agonist
|
[48]
|
|
2,4-dinitrophenol (DNP)
|
Antiseptic agent, pesticide, industrial chemical
|
Uncoupling oxidative phosphorylation
|
---
|
|
benz(a)anthracene (BAA)
|
Fossil fuels
|
DNA mutagen and Ah receptor agonist (PAH)
|
[49]
|
|
perfluorinated chemicals (PFC)
|
Industrial chemical
|
---
|
---
|
|
tert-Butylhydroquinone (TBHQ)
|
Ingredient in consumer products
|
---
|
---
|
|
Phenanthrene (PHE)
|
Fossil fuels
|
DNA mutagen and Ah receptor agonist (PAH)
|
[49]
|
|
Pyrene (PYR)
|
Fossil fuels
|
DNA mutagen and Ah receptor agonist (PAH)
|
[49]
|
|
decabromodiphenyl ether (BDE)
|
Flame retardant
| |
---
|
|
dibenzothiophene (DBT)
|
Fossil fuels
|
DNA mutagen and Ah receptor agonist (PAH)
|
[49]
|
|
17ß-estradiol (E2)
|
Endogenous estrogen
|
ER agonist
|
[18]
|
|
Diethylstilbestrol (DES)
|
medicine
|
ER agonist
|
---
|
|
ethniyl estradiol (EE2)
|
medicine
|
ER agonist
|
[18]
|
|
fadrozol (FAD)
|
medicine
|
CYP19 inhibitor
|
[18]
|
|
fipronil (FIP)
|
insecticide
|
GABA receptor antagonist
|
[18]
|
|
flutamide (FLU)
|
medicine
|
Androgen receptor antagonist
|
[18]
|
|
genistein (GEN)
|
phytoestrogen
|
ER and PPAR agonist
|
[50]
|
|
ketochonazole (KET)
|
medicine
|
CYP11A/CYP17 inhibitor
|
[18]
|
|
trenbolone (TRB)
|
Beef production
|
AR agonist
|
[18]
|
|
trilostane (TRI)
|
Veterinary medicine
|
3βHSD inhibitor
|
[18]
|
|
vinclozolin (VIN)
|
fungicide
|
AR antagonist (fungicide)
|
[18]
|
|
prochloraz (PRO)
|
fungicide
|
CYP17/19 inhibitor
|
[18]
|
|
muscimol (MUS)
|
research
|
GABA receptor agonist
|
[18]
|
|
bisphenol A (BPA)
|
Industrial chemical
|
ER agonist
|
[51]
|
|
Progesterone (PGST)
|
Endogenous hormone, medicine
|
PR agonist
|
[52]
|
|
Dihydrotestosterone (DHT)
|
Endogenous hormone
|
AR agonist
|
[53]
|
|
Haloperidol (HAL)
|
medicine
|
Dopamine D2 receptor antagonist
|
[54]
|
|
Diazepam (DIA)
|
medicine
|
GABA-A receptor modulator
|
[55]
|
|
bifenthrin (BIF)
|
insecticide
|
voltage-gated sodium channels disruption
|
[56]
|
|
cypermethrin (CYP)
|
insecticide
|
voltage-gated sodium channels disruption
|
[56]
|
|
esfenvalerate (ESF)
|
Insecticide
|
voltage-gated sodium channels disruption
|
[56]
|
|
Linuron (LIN)
|
Herbicide
|
photosynthesis inhibitor
|
[57]
|
|
Terbufos (TER)
|
Insecticide
|
acetylcholine esterase inhibitor
|
[58]
|
|
methylparaben (MPA)
|
Anti-fungal agent
|
Uncoupling oxidative phosphorylation
|
[59]
|
|
permethrin (PER)
|
Insecticide
|
voltage-gated sodium channels disruption
|
[56]
|
|
Propanil (PPL)
|
Herbicide
|
photosynthesis inhibitor
|
[60]
|
|
azinphos-methyl (APM)
|
Insecticide
|
acetylcholine esterase inhibitor
|
[61]
|
|
Propranolol (PPLL)
|
Medicine
|
β-adrenergic receptor antagonist
|
[62]
|
|
protein kinase C inhibitor 412 (PKC412)
|
Pharmaceutical compound
|
tyrosine kinase inhibitor
|
[63]
|
|
Triclocarban (TCC)
|
Anti-bacterial agent
|
---
|
---
|
|
Gemfibrozil (GEM)
|
Medicine
|
PPAR binding and activation
|
[64]
|
|
cyclotrimethylenetrinitramine (RDX)
|
Explosive
|
Neuro-toxin?
|
---
|
|
TNT
|
Explosive
|
---
|
---
|
|
Water samples near WWTPs
| | | |
|
Effluent; WWTP, San Diego, California (EFFLa, EFFHa)
|
Positive for GEM, DIA, E2, PGST
|
---
|
[29]
|
|
Effluent; WWTP, Los Angeles, California (EFFHb)
|
Positive for GEM, PGST
|
---
|
[29]
|
|
Effluent; WWTP, Duluth Minnesota (WLSSD)
|
Positive for various estrogens, BPA
|
---
|
Unpublished observations (Jenna Cavallin US EPA)
|
|
Upstream, effluent, downstream, WWTP, Ely Minnesota (ElyUS, ElyEFF, ElyDS)
|
At least one site positive for various estrogens, BPA, TCC, PAHs, chlorpyrifos
|
---
|
[30]
|
|
Upstream, effluent, downstream, WWTP, Hutchinson Minnesota (HutUS, HutEFF, HutDS)
|
At least one site positive for various estrogens, DES, BPA, TCC, PAHs, chlorpyrifos
|
---
|
[30]
|
|
Upstream, effluent, downstream, WWTP, Rochester Minnesota (RochUS, RochEFF, RochDS)
|
At least one site positive for various estrogens, BPA, TCC,
|
---
|
[30]
|
|
storm, stream, waste water; WWTP, Gainesville, Florida (stormH2O, strH2O, wasteH2O)
|
wasteH2O seasonally positive for BPA, DIA, PFCs
|
---
|
[65]
|
