Table 4 Top five significant hits, if any, of selected Cmap queries within microarray platforms
Signatures | 1st match | 2nd match | 3rd match | 4th match | 5th match |
|---|---|---|---|---|---|
|  | Within ZF 21K (p-value cutoff 1/45 = 0.022) | ||||
EE2_30ngL_Ovary_96hr | Self | FAD_Ovary | TRB_F_Brain | EE2_Testis | FAD_M_Brain |
EE2_30ngL_M_Brain_48hr | Self | EE2_Testis | FAD_M_Brain | TRB_F_Brain | EE2_Ovary |
EE2_30ngL_M_Liver_48hr | Self | TRB_F_Liver | EE2_Testis | O2_Testis | KET_M_Liver |
EE2_30ngL_Testis_48hr | Self | EE2_Ovary | EE2_M_Brain | FIP_F_Brain | TRI_TestisLow |
FAD_25ugL_F_Brain_48hr | Self | TRB_F_Brain | FAD_M_Brain | FAD_Ovary | EE2_Testis |
FAD_25ugL_Ovary_96hr | Self | EE2_Ovary | FAD_M_Brain | TRI_TestisLow | TRB_F_Brain |
FIP_5ugL_Testis_48hr | Self | FIP_Ovary | TRI_Testis | FIP_M_Brain | FLU_Testis |
FLU_1700ugL_Ovary_48hr | Self | FLU_Testis | PRO_Testis | VIN_Ovary | KET_Ovary |
MUS_500ugL_F_Brain_48hr | Self | VIN_Ovary | MUS_M_Brain | KET_M_Brain | VIN_Testis |
MUS_500ugL_M_Brain_48hr | Self | MUS_F_Brain | VIN_Ovary | KET_M_Brain | KET_Ovary |
O2_1mgL_Testis_4d | Self | O2_Ovary | EE2_M_Liver | O2_Ovary | VIN_Testis |
PRO_500ugL_F_Brain_48hr | FLU_Testis | self | PRO_Testis | VIN_Ovary | KET_Ovary |
PRO_500ugL_Ovary_48hr | Self | FLU_Ovary | FLU_Testis | KET_Ovary | PRO_Testis |
TCDD_2nM_Embryo_6h | Self | TCDD_Embryo | TRI_Ovary | O2_Ovary | PRO_Testis |
TRI_2500ugL_Testis_24hr | Self | VIN_Testis | VIN_Ovary | KET_Ovary | TRI_TestisLow |
VIN_1000ugL_Ovary_48hr | Self | KET_Ovary | TRI_Testis | VIN_Testis | FIP_Ovary |
VIN_1000ugL_Testis_48hr | Self | FLU_Testis | PRO_Testis | TRI_Testis | VIN_Ovary |
|  | Within ZF 43K (p-value cutoff 1/39 = 0.026) | ||||
BPA_0.01ugL_Ovary_96hr | Self | BPA_Ovary | BPA_Ovary | BPA_Ovary | BPA_Embryo |
E2_1uM_Embryo_4dpf | self | E2_M_Liver | GEN_Embryo | GEN_Embryo | FLU_Embryo |
EE2_0.65mgL_Embryo_48hr | EE2_Embryo | EE2_Embryo | GEN_Embryo | PARAB_Embryo | PYR_Embryo |
E2_5ugL_M_Liver_48hrs | self | E2_Embryo | PARAB_Embryo | PARAB_Embryo | GEN_Embryo |
GEN_2.4mgL_Embryo_48hr | self | GEN_Embryo | PARAB_Embryo | DBT_Embryo | diazepam_Brain |
PKC412_40ugL_fish_6dpf | PKC412_fish | self | RDX_fry | diazepam_Brain | RDX_fry |
PRO_500ugL_F_Brain_48hr | PRO_Ovary | linuron_Embryo | FLU_Ovary | PRO_F_Brain | linuron_Embryo |
PRO_500ugL_Ovary_48hr | self | FLU_Ovary | linuron_Embryo | PRO_F_Brain | linuron_Embryo |
RDX_7.5mgL_fry_96hr | self | RDX_fry | RDX_fry | RDX_fry | RDX_fry |
BPA_8mgL_Embryo_48hr | self | BPA_Embryo | EE2_Embryo | BAA_Embryo | PRO_Embryo |
diazepam_273ngL_brain_14d | self | diazepam_Brain | PKC412_fish | RDX_fry | RDX_fry |
linuron_1.2mgL_Embryo_48hr | self | linuron_Embryo | PKC412_fish | BPA_Embryo | diazepam_Brain |
PARAB_19.8mgL_Embryo_48hr | self | PARAB_Embryo | linuron_Embryo | linuron_Embryo | PYR_Embryo |
PRO_1.7mgL_Embryo_48hr | self | PRO_Embryo | E2_Embryo | BPA_Embryo | PARAB_Embryo |
|  | Within FHM 15K (p-value cutoff 1/132 = 0.0076) | ||||
BIF_0.15ugL_Larvae_48hr | BIF_Larvae | self | TER_M_Brain | Mixture_M_Brain | KETTNTKET_Ovary |
BIF_0.3ugL_Larvae_48hr | self | CYP_Larvae | ESF_Larvae | ESF_Larvae | PER_Larvae |
CYP_1ugL_Larvae_48hr | self | VZ_Ovary | PER_Larvae | CYP_larva | RDX_Ovary |
DES_1ngL_Liver_96h | EE2_Liver | self | PHE_High_Liver | E2_X_M_Liver | DES_Liver |
E2_4ugL_M_Liver_14d | self | E2_M_Liver | EE2_Liver | DES_Liver | ElyEFF_Liver |
EE2_25ngL_Liver_72h | E2_M_Liver | self | E2_X_M_Liver | DES_Liver | ElyEFF_Liver |
GEM_600ugL_Ovary_8d | self | GEM_Ovary | TrbEE2TrbEE2_Ovary | RochDS_Ovary | TrbEE2TRB_Ovary |
PHE_High_Liver_48hr | self | PHE_Med_Liver | ElyEFF_Liver | ElyUS_Liver | PFCs_Low_Liver |
TRB_30ngL_Ovary_24h | self | FLU_Ovary | TrbTCCTCC_Ovary | GEM_Ovary | GEM_Ovary |
TER_57.5ugL_M_Brain_72h | self | Mixture_M_Brain | PER_M_Brain | BIF_Larvae | KET_Ovary |