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Table 5 Identification of genes of interest from TBI-C network analysis

From: Bilateral gene interaction hierarchy analysis of the cell death gene response emphasizes the significance of cell cycle genes following unilateral traumatic brain injury

Network ID GOI found Total # of GOI Overlap with previous analyses Net # of GOI Top molecular types
1 ACIN1 , ACVR1C, CD44 , DPYD, FGL2 , MAPK8 , MTDH, RAD23B, TTLL1 9 4 5 enzymes and kinases
2 AURKAIP1, BTG2 , CCND1 , LCN2 , MAFG, PIK3CD, PIK3R2, RND3 , SETD8 , SOX2, TRPM7, ZMYND11, ZNF148 13 5 8 transcription regulators, kinases, and enzymes
3 AHI1 , CDK11A , CDK19, DNAJB6 , HSP90AA1, HSPB1 , KLF13 , LINGO1, MED1, PA2G4 , PPP3CB, THRA , TUFM 13 7 6 transcription regulators, undefined, and kinases
4 EIF5B , ENTPD5, FOXO1, KRAS , MEF2A, PALLD, PRKAA2, PTK2B, RASSF4 , Serbp 10 3 7 undefined, transcription regulators, enzymes, and kinases
5 ATP2A2, ATP2B2, BAX , CDH13, GBX2, GSK3B , KCND2 , MAFB, MFN1, NDUFAB1, PRKAA2 11 4 7 transporters, kinases, enzymes, and undefined
6 CCDC86, CCND2, CEBPD , GSK3B , PRLR, PSIP1 , RSF1, SP1, SPP1 , TIMP1 10 5 5 transcription regulators, undefined, and cytokines
  1. Italics= > gene of interest also found in a previous analysis; Bold= > GOI unique to this analysis