Primary
| | | | |
ATF3
|
activating transcription factor 3
|
12.027
|
Nucleus
|
transcription regulator
|
CCND1
|
cyclin D1
|
2.152
|
Nucleus
|
transcription regulator
|
CEBPB
|
CCAAT/enhancer binding protein (C/EBP), beta
|
3.366
|
Nucleus
|
transcription regulator
|
CREB1
|
cAMP responsive element binding protein 1
|
2.666
|
Nucleus
|
transcription regulator
|
CREBBP
|
CREB binding protein
|
2.421
|
Nucleus
|
transcription regulator
|
MDM2
|
MDM2 proto-oncogene, E3 ubiquitin protein ligase
|
2.01
|
Nucleus
|
transcription regulator
|
NFE2L2
|
nuclear factor, erythroid 2-like 2
|
2.452
|
Nucleus
|
transcription regulator
|
SMARCA4
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
|
2.521
|
Nucleus
|
transcription regulator
|
STAT3
|
signal transducer and activator of transcription 3 (acute-phase response factor)
|
4.219
|
Nucleus
|
transcription regulator
|
CDK1
|
cyclin-dependent kinase 1
|
2.105
|
Nucleus
|
kinase
|
CSNK2A1
|
casein kinase 2, alpha 1 polypeptide
|
2.992
|
Cytoplasm
|
kinase
|
EGFR
|
epidermal growth factor receptor
|
6.773
|
Plasma Membrane
|
kinase
|
GSK3B
|
glycogen synthase kinase 3 beta
|
−2.733
|
Nucleus
|
kinase
|
CD44
|
CD44 molecule (Indian blood group)
|
15.558
|
Plasma Membrane
|
enzyme
|
FN1
|
fibronectin 1
|
3.97
|
Extracellular Space
|
enzyme
|
TRAF6
|
TNF receptor-associated factor 6, E3 ubiquitin protein ligase
|
2.163
|
Cytoplasm
|
enzyme
|
CASP3
|
caspase 3, apoptosis-related cysteine peptidase
|
2.535
|
Cytoplasm
|
peptidase
|
ELAVL1
|
ELAV like RNA binding protein 1
|
3.275
|
Cytoplasm
|
other
|
Secondary
| | | | |
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
11.271
|
Nucleus
|
transcription regulator
|
CREM
|
cAMP responsive element modulator
|
2.165
|
Nucleus
|
transcription regulator
|
EGR2
|
early growth response 2
|
2.271
|
Nucleus
|
transcription regulator
|
FOSL1
|
FOS-like antigen 1
|
5.875
|
Nucleus
|
transcription regulator
|
KLF4
|
Kruppel-like factor 4 (gut)
|
2.057
|
Nucleus
|
transcription regulator
|
MITF
|
microphthalmia-associated transcription factor
|
4.755
|
Nucleus
|
transcription regulator
|
TCF4
|
transcription factor 4
|
−2.216
|
Nucleus
|
transcription regulator
|
HSPA1A/HSPA1B
|
heat shock 70 kDa protein 1A
|
3.137
|
Cytoplasm
|
enzyme
|
MCM2
|
minichromosome maintenance complex component 2
|
2.57
|
Nucleus
|
enzyme
|
PTGS2
|
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
|
3.106
|
Cytoplasm
|
enzyme
|
IL1B
|
interleukin 1, beta
|
5.166
|
Extracellular Space
|
cytokine
|
SPP1
|
secreted phosphoprotein 1
|
37.905
|
Extracellular Space
|
cytokine
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
3.732
|
Nucleus
|
kinase
|
IKBKB
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
|
2.127
|
Cytoplasm
|
kinase
|
KPNB1
|
karyopherin (importin) beta 1
|
3.173
|
Nucleus
|
transporter
|
MCL1
|
myeloid cell leukemia 1
|
3.25
|
Cytoplasm
|
transporter
|
THRA
|
thyroid hormone receptor, alpha
|
−2.799
|
Nucleus
|
ligand-dependent nuclear receptor
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
2.579
|
Cytoplasm
|
peptidase
|
BAG3
|
BCL2-associated athanogene 3
|
4.045
|
Cytoplasm
|
other
|
CCNA2
|
cyclin A2
|
2.633
|
Nucleus
|
other
|
GFAP
|
glial fibrillary acidic protein
|
3.011
|
Cytoplasm
|
other
|
HSPA9
|
heat shock 70 kDa protein 9 (mortalin)
|
2.666
|
Cytoplasm
|
other
|
HSPB1
|
heat shock 27 kDa protein 1
|
46.922
|
Cytoplasm
|
other
|
SNCA
|
synuclein, alpha (non A4 component of amyloid precursor)
|
−2.169
|
Cytoplasm
|
other
|
Peripheral
| | | | |
ACSL5
|
acyl-CoA synthetase long-chain family member 5
|
−2.361
|
Cytoplasm
|
enzyme
|
ANXA1
|
annexin A1
|
3.535
|
Plasma Membrane
|
enzyme
|
CHSY1
|
chondroitin sulfate synthase 1
|
2.873
|
Cytoplasm
|
enzyme
|
CP
|
ceruloplasmin (ferroxidase)
|
27.838
|
Extracellular Space
|
enzyme
|
EHD4
|
EH-domain containing 4
|
2.361
|
Plasma Membrane
|
enzyme
|
GCLM
|
glutamate-cysteine ligase, modifier subunit
|
2.019
|
Cytoplasm
|
enzyme
|
HMOX1
|
heme oxygenase (decycling) 1
|
9.778
|
Cytoplasm
|
enzyme
|
MCM8
|
minichromosome maintenance complex component 8
|
2.027
|
Nucleus
|
enzyme
|
MX1
|
MX dynamin-like GTPase 1
|
28.177
|
Cytoplasm
|
enzyme
|
PDE4B
|
phosphodiesterase 4B, cAMP-specific
|
5.602
|
Cytoplasm
|
enzyme
|
RAB35
|
RAB35, member RAS oncogene family
|
2.086
|
Cytoplasm
|
enzyme
|
RRM2
|
ribonucleotide reductase M2
|
3.34
|
Nucleus
|
enzyme
|
SDC1
|
syndecan 1
|
13.681
|
Plasma Membrane
|
enzyme
|
SETD8
|
SET domain containing (lysine methyltransferase) 8
|
2.029
|
Nucleus
|
enzyme
|
SGPL1
|
sphingosine-1-phosphate lyase 1
|
3.108
|
Cytoplasm
|
enzyme
|
SRXN1
|
sulfiredoxin 1
|
6.306
|
Cytoplasm
|
enzyme
|
TGM2
|
transglutaminase 2
|
3.574
|
Cytoplasm
|
enzyme
|
TOP2A
|
topoisomerase (DNA) II alpha 170 kDa
|
2.26
|
Nucleus
|
enzyme
|
BCL11A
|
B-cell CLL/lymphoma 11A (zinc finger protein)
|
−2.38
|
Nucleus
|
transcription regulator
|
BTG2
|
BTG family, member 2
|
−2.22
|
Nucleus
|
transcription regulator
|
CCAR1
|
cell division cycle and apoptosis regulator 1
|
−2.943
|
Nucleus
|
transcription regulator
|
CSRNP1
|
cysteine-serine-rich nuclear protein 1
|
2.821
|
Nucleus
|
transcription regulator
|
DEK
|
DEK proto-oncogene
|
−3.006
|
Nucleus
|
transcription regulator
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
−4.383
|
Nucleus
|
transcription regulator
|
ETV5
|
ets variant 5
|
−2.163
|
Nucleus
|
transcription regulator
|
KLF13
|
Kruppel-like factor 13
|
−2.006
|
Nucleus
|
transcription regulator
|
KLF6
|
Kruppel-like factor 6
|
6.003
|
Nucleus
|
transcription regulator
|
NAA15
|
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
|
3.605
|
Nucleus
|
transcription regulator
|
NFIX
|
nuclear factor I/X (CCAAT-binding transcription factor)
|
−2.548
|
Nucleus
|
transcription regulator
|
NFKB2
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
|
2.768
|
Nucleus
|
transcription regulator
|
PA2G4
|
proliferation-associated 2G4, 38 kDa
|
−2.702
|
Nucleus
|
transcription regulator
|
PRDM2
|
PR domain containing 2, with ZNF domain
|
3.677
|
Nucleus
|
transcription regulator
|
TBL1XR1
|
transducin (beta)-like 1 X-linked receptor 1
|
2.587
|
Nucleus
|
transcription regulator
|
TCEB3
|
transcription elongation factor B (SIII), polypeptide 3 (110 kDa, elongin A)
|
3.053
|
Nucleus
|
transcription regulator
|
CAMK1G
|
calcium/calmodulin-dependent protein kinase IG
|
−2.271
|
Cytoplasm
|
kinase
|
CAMK2N1
|
calcium/calmodulin-dependent protein kinase II inhibitor 1
|
−11.813
|
Plasma Membrane
|
kinase
|
CARD11
|
caspase recruitment domain family, member 11
|
7.343
|
Cytoplasm
|
kinase
|
CDK11A
|
cyclin-dependent kinase 11A
|
−4.29
|
Nucleus
|
kinase
|
FGR
|
FGR proto-oncogene, Src family tyrosine kinase
|
3.915
|
Nucleus
|
kinase
|
HCK
|
HCK proto-oncogene, Src family tyrosine kinase
|
3.887
|
Cytoplasm
|
kinase
|
HSPB8
|
heat shock 22 kDa protein 8
|
4.112
|
Cytoplasm
|
kinase
|
LATS1
|
large tumor suppressor kinase 1
|
2.003
|
Nucleus
|
kinase
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
2.258
|
Cytoplasm
|
kinase
|
NEK6
|
NIMA-related kinase 6
|
2.322
|
Nucleus
|
kinase
|
SRPK2
|
SRSF protein kinase 2
|
−5.614
|
Nucleus
|
kinase
|
TJP2
|
tight junction protein 2
|
2.552
|
Plasma Membrane
|
kinase
|
Ccl2
|
chemokine (C-C motif) ligand 2
|
195.455
|
Extracellular Space
|
cytokine
|
CCL3L3
|
chemokine (C-C motif) ligand 3-like 3
|
5.269
|
Extracellular Space
|
cytokine
|
CCL4
|
chemokine (C-C motif) ligand 4
|
2.162
|
Extracellular Space
|
cytokine
|
Ccl6
|
chemokine (C-C motif) ligand 6
|
10.291
|
Extracellular Space
|
cytokine
|
Ccl7
|
chemokine (C-C motif) ligand 7
|
124.78
|
Extracellular Space
|
cytokine
|
CXCL3
|
chemokine (C-X-C motif) ligand 3
|
13.211
|
Extracellular Space
|
cytokine
|
Cxcl9
|
chemokine (C-X-C motif) ligand 9
|
2.846
|
Extracellular Space
|
cytokine
|
TIMP1
|
TIMP metallopeptidase inhibitor 1
|
38.486
|
Extracellular Space
|
cytokine
|
IL6R
|
interleukin 6 receptor
|
2.315
|
Plasma Membrane
|
transmembrane receptor
|
IL6ST
|
interleukin 6 signal transducer
|
2.307
|
Plasma Membrane
|
transmembrane receptor
|
ITGB2
|
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
|
2.675
|
Plasma Membrane
|
transmembrane receptor
|
TLR4
|
toll-like receptor 4
|
2.699
|
Plasma Membrane
|
transmembrane receptor
|
TNFRSF1A
|
tumor necrosis factor receptor superfamily, member 1A
|
3.555
|
Plasma Membrane
|
transmembrane receptor
|
UNC5B
|
unc-5 homolog B (C. elegans)
|
2.067
|
Plasma Membrane
|
transmembrane receptor
|
ALB
|
albumin
|
−3.125
|
Extracellular Space
|
transporter
|
LCN2
|
lipocalin 2
|
71.824
|
Extracellular Space
|
transporter
|
RASA1
|
RAS p21 protein activator (GTPase activating protein) 1
|
2.392
|
Cytoplasm
|
transporter
|
TPR
|
translocated promoter region, nuclear basket protein
|
2.212
|
Nucleus
|
transporter
|
FGL2
|
fibrinogen-like 2
|
16.793
|
Extracellular Space
|
peptidase
|
SENP2
|
SUMO1/sentrin/SMT3 specific peptidase 2
|
2.051
|
Nucleus
|
peptidase
|
DUSP5
|
dual specificity phosphatase 5
|
3.285
|
Nucleus
|
phosphatase
|
PTPRF
|
protein tyrosine phosphatase, receptor type, F
|
−6.365
|
Plasma Membrane
|
phosphatase
|
EIF3C
|
eukaryotic translation initiation factor 3, subunit C
|
−4.369
|
Other
|
translation regulator
|
EIF5B
|
eukaryotic translation initiation factor 5B
|
−3.044
|
Cytoplasm
|
translation regulator
|
FGF2
|
fibroblast growth factor 2 (basic)
|
2.387
|
Extracellular Space
|
growth factor
|
KCND2
|
potassium voltage-gated channel, Shal-related subfamily, member 2
|
−2.792
|
Plasma Membrane
|
ion channel
|
AHI1
|
Abelson helper integration site 1
|
2.243
|
Cytoplasm
|
other
|
BCL2A1
|
BCL2-related protein A1
|
3.055
|
Cytoplasm
|
other
|
CALB1
|
calbindin 1, 28 kDa
|
−2.091
|
Cytoplasm
|
other
|
CD68
|
CD68 molecule
|
4.365
|
Plasma Membrane
|
other
|
CDCA7L
|
cell division cycle associated 7-like
|
2.648
|
Nucleus
|
other
|
CDT1
|
chromatin licensing and DNA replication factor 1
|
3.098
|
Nucleus
|
other
|
CISD2
|
CDGSH iron sulfur domain 2
|
−7.833
|
Cytoplasm
|
other
|
CMIP
|
c-Maf inducing protein
|
−3.778
|
Cytoplasm
|
other
|
DAB2
|
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
|
3.053
|
Plasma Membrane
|
other
|
DES
|
desmin
|
2.857
|
Cytoplasm
|
other
|
DNAJB9
|
DnaJ (Hsp40) homolog, subfamily B, member 9
|
2.128
|
Nucleus
|
other
|
FLNA
|
filamin A, alpha
|
3.45
|
Cytoplasm
|
other
|
GADD45G
|
growth arrest and DNA-damage-inducible, gamma
|
3.191
|
Nucleus
|
other
|
HLA-A
|
major histocompatibility complex, class I, A
|
9.296
|
Plasma Membrane
|
other
|
HSPA2
|
heat shock 70 kDa protein 2
|
3.51
|
Cytoplasm
|
other
|
LCP1
|
lymphocyte cytosolic protein 1 (L-plastin)
|
6.082
|
Cytoplasm
|
other
|
LSP1
|
lymphocyte-specific protein 1
|
11.716
|
Cytoplasm
|
other
|
MMS22L
|
MMS22-like, DNA repair protein
|
2.918
|
Nucleus
|
other
|
MSI2
|
musashi RNA-binding protein 2
|
2.288
|
Cytoplasm
|
other
|
PDLIM7
|
PDZ and LIM domain 7 (enigma)
|
4.695
|
Cytoplasm
|
other
|
PHLDA1
|
pleckstrin homology-like domain, family A, member 1
|
5.129
|
Cytoplasm
|
other
|
PMEPA1
|
prostate transmembrane protein, androgen induced 1
|
2.682
|
Plasma Membrane
|
other
|
PSIP1
|
PC4 and SFRS1 interacting protein 1
|
−2.663
|
Nucleus
|
other
|
RDX
|
radixin
|
4.828
|
Cytoplasm
|
other
|
SERPINA3
|
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
|
58.488
|
Extracellular Space
|
other
|
SPIN1
|
spindlin 1
|
2.178
|
Nucleus
|
other
|
SUDS3
|
suppressor of defective silencing 3 homolog (S. cerevisiae)
|
2.228
|
Nucleus
|
other
|
TAGLN2
|
transgelin 2
|
3.891
|
Cytoplasm
|
other
|
THOC2
|
THO complex 2
|
2.119
|
Nucleus
|
other
|
TMEM109
|
transmembrane protein 109
|
2.106
|
Cytoplasm
|
other
|
TMEM123
|
transmembrane protein 123
|
2.348
|
Plasma Membrane
|
other
|
Orphan
| | | | |
CYP1B1
|
cytochrome P450, family 1, subfamily B, polypeptide 1
|
10.998
|
Cytoplasm
|
enzyme
|
KIF3A
|
kinesin family member 3A
|
−5.083
|
Cytoplasm
|
enzyme
|
PTGR1
|
prostaglandin reductase 1
|
2.258
|
Cytoplasm
|
enzyme
|
RND3
|
Rho family GTPase 3
|
2.864
|
Cytoplasm
|
enzyme
|
WFS1
|
Wolfram syndrome 1 (wolframin)
|
2.083
|
Cytoplasm
|
enzyme
|
ITPR2
|
inositol 1,4,5-trisphosphate receptor, type 2
|
2.489
|
Cytoplasm
|
ion channel
|
KCNN4
|
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
|
3.088
|
Plasma Membrane
|
ion channel
|
ATRX
|
alpha thalassemia/mental retardation syndrome X-linked
|
2.091
|
Nucleus
|
transcription regulator
|
RAI14
|
retinoic acid induced 14
|
3.284
|
Nucleus
|
transcription regulator
|
CX3CL1
|
chemokine (C-X3-C motif) ligand 1
|
−2.044
|
Extracellular Space
|
cytokine
|
PTGER3
|
prostaglandin E receptor 3 (subtype EP3)
|
2.425
|
Plasma Membrane
|
G-protein coupled receptor
|
PI4K2A
|
phosphatidylinositol 4-kinase type 2 alpha
|
2.96
|
Cytoplasm
|
kinase
|
CD36
|
CD36 molecule (thrombospondin receptor)
|
5.08
|
Plasma Membrane
|
transmembrane receptor
|
ARL11
|
ADP-ribosylation factor-like 11
|
3.143
|
Other
|
other
|
Brd4
|
bromodomain containing 4
|
−3.528
|
Nucleus
|
other
|
CLN5
|
ceroid-lipofuscinosis, neuronal 5
|
2.041
|
Cytoplasm
|
other
|
Ctdspl
|
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
|
−7.271
|
Cytoplasm
|
other
|
KIFAP3
|
kinesin-associated protein 3
|
−2.281
|
Cytoplasm
|
other
|
Nos1ap
|
nitric oxide synthase 1 (neuronal) adaptor protein
|
−2.698
|
Other
|
other
|
PCDH15
|
protocadherin-related 15
|
2.147
|
Plasma Membrane
|
other
|
RASSF4
|
Ras association (RalGDS/AF-6) domain family member 4
|
4.289
|
Other
|
other
|
Rbm25
|
RNA binding motif protein 25
|
−5.547
|
Nucleus
|
other
|
Slpi
|
secretory leukocyte peptidase inhibitor
|
82.908
|
Cytoplasm
|
other
|
Tpm3
|
tropomyosin 3
|
2.592
|
Cytoplasm
|
other
|
TRIM54
|
tripartite motif containing 54
|
−4.426
|
Cytoplasm
|
other
|