Fig. 4

Genes expressed at different levels in HK (a) and liver (b) upon dietary supplementation with Sel-Plex and immune challenges. The Venn diagram shows the genes identified by microarray analysis significantly altered in expression as tested by one-way ANOVA and Tukey’s HSD multiple comparisons test (p < 0.05 and Benjamini-Hochberg correction), with ≥2 fold change in expression. The genes up-regulated and down-regulated in the group fed the 4 mg Kg⁻¹ Sel-Plex enriched diet relative to the group fed a control diet are named SeC. The genes up-regulated and down-regulated in the group fed a control diet or a 4 mg Se Kg⁻¹ enriched diet and injected with poly(I:C), relative to the same diet groups injected with PBS, are indicated as CP and SeP respectively