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Table 4 GO function terms were enriched within genes with hypermethylated a-CpGs in the analysis with GOrilla. Table contains the full list of enriched GO function terms (Bonferroni-adjusted p < 0.05) obtained from analysis with GOrilla [21, 43]

From: Aging-associated DNA methylation changes in middle-aged individuals: the Young Finns study

GO term Description of the function p-value (-log10)
GO:0043565 Sequence-specific DNA binding 10.001
GO:0000981 Sequence-specific DNA binding RNA polymerase II transcription factor activity 7.322
GO:0001071 Nucleic acid binding transcription factor activity 6.721
GO:0003700 Sequence-specific DNA binding transcription factor activity 6.721
GO:0003677 DNA binding 6.625
GO:0005326 Neurotransmitter transporter activity 5.148
GO:0005488 Binding 4.967