Table 7 aTop canonical pathways up-regulated by differentially expressed genes in mammary glands of cows whose diets were supplemented with 5Â % linseed oil or 5Â % safflower oil
Experimental periods compared | Linseed oil treatment | Â | Â | Safflower oil treatment | Â | Â |
|---|---|---|---|---|---|---|
Top Canonical pathways | P-value | FDR BH P-value | Top Canonical pathways | P-value | FDR BH P-value | |
Day-14 vs day+7 | Complement System | 1.27E-05 | 4.75E-03 | - | - | - |
| Â | UDP-N-acetyl-D-glucosamine Biosynthesis II | 1.94E-04 | 3.63E-02 | - | - | - |
| Â | UDP-N-acetyl-D-galactosamine Biosynthesis II | 7.75E-04 | 8.68E-02 | - | - | - |
| Â | Unfolded protein response | 1.08E-03 | 8.68E-02 | - | - | - |
| Â | Antigen Presentation Pathway | 1.16E-03 | 8.68E-02 | - | - | - |
Day+7 vs day+28 | Role of Tissue Factor in Cancer | 7.81E-05 | 2.93E-02 | Mitochondrial Dysfunction | 1.42E-04 | 2.54E-02 |
| Â | FXR/RXR Activation | 1.11E-03 | 2.11E-01 | Antioxidant Action of Vitamin C | 4.82E-04 | 3.50E-02 |
| Â | Arginine Degradation I (Arginase Pathway) | 2.37E-03 | 2.42E-01 | Zymosterol Biosynthesis | 6.37E-04 | 3.50E-02 |
| Â | Growth Hormone Signaling | 2.67E-03 | 2.42E-01 | Oxidative Phosphorylation | 7.83E-04 | 3.50E-02 |
| Â | bLXR/RXR Activation | 3.18E-03 | 2.42E-01 | LXR/RXR Activation | 1.25E-03 | 4.48E-02 |
Day-14 vs day+28 | Oncostatin M Signaling | 1.18E-04 | 4.19E-02 | Oncostatin M Signaling | 4.71E-04 | 1.77E-02 |
| Â | IL-22 Signaling | 7.43E-04 | 5.21E-02 | IL-22 Signaling | 1.65E-04 | 1.29E-02 |
| Â | Role of JAK family kinases in IL-6-type Cytokine Signaling | 8.40E-04 | 5.21E-02 | Role of JAK family kinases in IL-6-type Cytokine Signaling | 1.86E-04 | 1.29E-02 |
| Â | TR/RXR Activation | 6.44E-04 | 5.21E-02 | Role of JAK2 in Hormone-like Cytokine Signaling | 5.13E-04 | 1.77E-02 |
| Â | Unfolded protein response | 7.16E-04 | 5.21E-02 | Antioxidant Action of Vitamin C | 9.88E-04 | 2.73E-02 |