Fig. 3

Differentially expressed genes that were either up- or down-regulated in response to increasing fat intake. Results were obtained using the limma library, modeling gene expression as a function of raw fat intake data (i.e., linear model), logarithm-, exponential-, quadratic- or cubic-transformed fat intake values; adjusted p-value < 0.1. In each plot, y-axis represents the gene count and x-axis corresponds to response types (linear, logarithmic, exponential, quadratic and cubic). Results refer to three sections of small intestine: a proximal; b middle; and c distal