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Fig. 1 | BMC Genomics

Fig. 1

From: The effects of sample size on population genomic analyses – implications for the tests of neutrality

Fig. 1

Differential effects of sample size on the estimation of θ using the number of synonymous (θ S ) and nonsynonymous (θ N ) segregating sites. a Relationship between the sample size and θ. The relationships were significant (P < 0.01) based on the Pearson correlation as well as the non-parametric Kendal rank correlation using the log-transformed values of X and Y data points. Best fitting regression lines are shown. X and Y axes are in log-log scales (base 2). b Correlation between the number of exomes and the ratio of θ S /θ N . The relationship was statistically significant (P < 0.01). c The fraction of nonsynonymous variants observed using various sample sizes of human exomes. The error bars denote the standard error estimated using the binomial variance

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