Fig. 5
Heatmap–metabolic processes: this heatmap demonstrates the change in expression patterns of metabolic genes that displayed differential expression in at least one acclimation time point (7d, 28d, or 56d) when fish acclimated to the multi-stressor treatment (n = 4) were compared to fish in the control treatments (n = 4). Genes associated with the gene ontology term carbohydrate metabolic process (GO:0005975) are represented by (+) and lipid metabolic process (GO:0006629) are represented by (=) . Fold change is log2 adjusted with genes showing significant up-regulation depicted in yellow and genes showing a significant down-regulation in blue (FDR ≤ 0.05). Genes whose level of expression did not differ significantly between control and multi-stressor treatments are shown in white. The number of gene variants identified in the annotated transcriptome that were associated with the same gene name are indicated in parentheses next the gene symbol