Fig. 5
From: Dissecting genetics of cutaneous miRNA in a mouse model of an autoimmune blistering disease
Boxplot for genotype variations for significant SNP in miRNA eQTL for disease QTL. The figure describes the genotype variation for the peak SNP for miRNAs mapped to the previously described EBA QTL. a) In miR-130b eQTL, peak SNP (rs6413270, −logP = 4.22) have genotype AA for BxD2 and CAST/EiJ while BB for NZM/2410J and MRL/MpJ strain. The variation associated with three genotypes AA, AB and BB for expression of miR-130b is presented on left and onset week of EBA on right box. b) In miR-493 eQTL, peak SNP (rs6211533, −logP = 4.99) have genotype AA for BxD2, CAST/EiJ and NZM/2410J while BB for MRL/MpJ strain. The variation associated with three genotypes AA, AB and BB for expression of miR-493 is on left, maximum score of severity of EBA disease in middle and onset week of EBA on right