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Fig. 7 | BMC Genomics

Fig. 7

From: Photoreceptor proliferation and dysregulation of cell cycle genes in early onset inherited retinal degenerations

Fig. 7

Immunolabeling in normal and mutant retinas for retinal transcription factors. A CRX; B NRL; C PAX6. Samples were from normal (7 wks), xlpra2 (8 wks), rcd1 (7 wks) and erd (CRX-9.1 wks; NRL-7.7 wks; PAX6-14.1 wks). In normal, xlpra2 and rcd1, NRL is expressed in cone outer segments (B1 arrowheads and corresponding locations in B2 and B3) and in the basal aspect of the outer nuclear layer; the rcd1 retina has few rods, and almost no rod outer segments remain so NRL distinctly labels the surviving cone outer segments. PR = photoreceptor, ONL = outer nuclear layer, INL = inner nuclear layer, IPL = inner plexiform layer, NFL = nerve fiber layer. Scale bar = 40 μm

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BMC Genomics

ISSN: 1471-2164

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