Skip to main content
Fig. 8 | BMC Genomics

Fig. 8

From: Photoreceptor proliferation and dysregulation of cell cycle genes in early onset inherited retinal degenerations

Fig. 8

Immunolabeling in normal and mutant retinas for selected cell cycle proteins. Paired sections from normal, xlpra2, rcd1, erd retina taken at two ages were labeled with antibodies against: A E2F1, B CCND1, C CCNE1. More intense labeling of the RPE layer is present in mutants compared with normals with antibodies against E2F1 and CCND1. Note that in the 16 wk xlpra2 retina (B2), the RPE layer has separated from the section during immunolabeling and is not included in the image. RPE = retinal pigment epithelium, ONL = outer nuclear layer, OPL = outer plexiform layer, INL = inner nuclear layer, IPL = inner plexiform layer, NFL = nerve fiber layer. Scale bar = 40 μm

Back to article page

BMC Genomics

ISSN: 1471-2164

Contact us