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Fig. 4 | BMC Genomics

Fig. 4

From: Ultra-precise detection of mutations by droplet-based amplification of circularized DNA

Fig. 4

Detected mutation number, FPR and FNR of 3 pg Droplet-CirSeq and 3 pg Cir-seq libraries. a, b The number of gold standard SNPs detected by Droplet-CirSeq and Cir-seq methods with different CSs (consensus sequences) numbers at “1X allele” and “2X allele” criterion (*: 0.01 = <p < 0.05, **: 0.001 = <p < 0.01, ***: p < 0.001). c, d FPR of 3 pg input Droplet-CirSeq and Cir-seq libraries at “1X allele” and “2X allele” criterion. e, f FNR of 3 pg input Droplet-CirSeq and Cir-seq libraries at “1X allele” and “2X allele” criterion

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