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Fig. 4 | BMC Genomics

Fig. 4

From: Genome-wide association study using family-based cohorts identifies the WLS and CCDC170/ESR1 loci as associated with bone mineral density

Fig. 4

Regional association plots for the CCDC170 locus for (a) spine, (b) femoral neck and (c) total hip BMD. Genetic variants within 200 kb of the CCDC170 gene are depicted (x axis) along with their meta-analysis P value (−log10). Variants are colour coded according to their LD (r2) with the lead SNP (1000 Genomes Project Nov 2014 EUR population). The red bars represent the gene-wide region tested and association P value (−log10). The recombination rate (blue line) and position of genes, their exons and direction of transcription is also indicated [69]

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BMC Genomics

ISSN: 1471-2164

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