Fig. 4

Increase in relative lung weight after influenza A H3N2 infection. Eight to twelve weeks old female mice of the eight CC founder strains were infected intra-nasally with 1 × 10¹ FFU of the mouse-adapted influenza H3N2 virus (A/HK/01/68). Lung weight was determined on day 3, 5, 8, 18 and 30 p.i. and for mock infected animals on day 3 post PBS treatment. CC founder strains showed comparable increase in relative lung weight up to 2 % except for the highly resistant NZO/HlLtJ and PWK/PhJ. Each data point represents the measurement of one animal. Additionally, the mean and the standard error of the mean are shown for each time point and strain