From: Detailed phenotyping identifies genes with pleiotropic effects on body composition
Group 1a | Group 2a | Group 3a | Group 4a | Group 5a | |||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lead SNP orderb | 1st | 2nd | 3rd | 4th | 5th | 6th | 7th | 8th | 9th | 10th | 11th | 12th | 13th | 14th | 15th | 16th | 17th | 18th | 19th | 20th | 21st | 22nd | 23rd |
PSWT | 1.8 | 8.3 | 6.3 | 2.4 | −1.8 | 3.7 | 2.3 | 2.3 | −1.4 | 2.2 | |||||||||||||
HCWT | 5.6 | 1.6 | 1.3 | −1.4 | 1.1 | 3.0 | 1.0 | 4.0 | |||||||||||||||
LLWT | 1.4 | 1.6 | 1.1 | 2.1 | 3.1 | 6.5 | −1.3 | 1.6 | −1.7 | 1.3 | |||||||||||||
TOP | 2.0 | 3.4 | 5.5 | −1.2 | −1.8 | 2.9 | 2.4 | 3.3 | 1.2 | −1.6 | 1.4 | 2.5 | |||||||||||
RND | 2.5 | 7.2 | 8.1 | −1.7 | 3.1 | 1.9 | 1.4 | −1.0 | −1.0 | 2.5 | |||||||||||||
BONE | 2.7 | 2.7 | 10.9 | 13.7 | 2.2 | 2.6 | 1.3 | −2.2 | 1.7 | 1.2 | |||||||||||||
LEGBONE | 5.7 | 2.4 | 12.3 | 19.1 | −1.3 | 2.7 | −1.6 | −1.1 | −1.0 | 2.3 | |||||||||||||
LMY | 3.3 | 1.2 | 5.0 | 8.7 | 1.2 | −1.5 | 1.9 | −1.2 | 2.9 | 1.8 | −2.5 | −2.5 | −1.0 | ||||||||||
DRESS% | −3.6 | −3.1 | −3.4 | −8.7 | −2.4 | 1.2 | 1.1 | −1.6 | −1.3 | 1.5 | 4.7 | ||||||||||||
DMLOIN | −1.2 | −2.6 | −6.4 | −2.1 | −1.3 | −2.1 | 2.7 | 1.9 | 1.1 | ||||||||||||||
IMF | −1.7 | −1.8 | −4.0 | 2.2 | −1.8 | −2.0 | −5.9 | −1.6 | 2.7 | 1.3 | −1.4 | −1.5 | 1.2 | −1.3 | |||||||||
LLFAT | −2.5 | −4.1 | −6.4 | 2.0 | 1.8 | 1.7 | 1.9 | 1.1 | 2.5 | 3.2 | 2.7 | ||||||||||||
CFATSCORE | −2.4 | 1.1 | −4.1 | −4.0 | 1.1 | 1.2 | 1.4 | −1.5 | −1.4 | 2.0 | |||||||||||||
CCFAT | −2.5 | −2.9 | −3.1 | −9.2 | 3.0 | 1.4 | −2.1 | 1.9 | −1.7 | 1.2 | −1.5 | −1.7 | 1.3 | ||||||||||
HGRFAT | −3.4 | −1.9 | −7.1 | −9.3 | 1.8 | 2.2 | −2.0 | 1.6 | 1.3 | −1.5 | 1.9 | 1.5 | 1.5 | 1.0 | |||||||||
CFAT5 | −2.2 | −2.2 | −4.6 | −4.6 | −2.0 | 2.0 | 1.4 | 1.9 | −1.2 | −1.5 | 2.9 | ||||||||||||
CEMW | 2.1 | 1.2 | 5.4 | 1.1 | 1.2 | 1.1 | −2.2 | −1.9 | 2.3 | ||||||||||||||
CEMD | −2.9 | −1.8 | −5.0 | −3.8 | 1.4 | 3.7 | 1.5 | −2.5 | 1.6 | 1.6 | −1.5 | ||||||||||||
CEMA | −1.0 | −1.9 | −3.4 | 1.1 | 2.7 | 1.6 | 2.0 | −3.5 | 1.0 | −1.6 | 1.9 | ||||||||||||
SHEARF5 | 2.5 | 1.2 | 3.3 | 3.7 | 1.2 | −1.0 | −3.4 | −2.6 | 8.0 | 5.6 | 1.2 | −1.1 | 1.8 | 1.2 | −4.5 | ||||||||
SHEARF1 | 2.7 | 1.8 | 1.1 | 1.8 | 1.4 | −1.2 | −2.4 | −1.3 | 5.5 | 3.3 | −1.5 | −1.3 | 2.6 | −1.3 | |||||||||
MYOGLOBIN | 2.4 | −2.3 | −3.6 | −1.3 | 5.4 | 5.5 | 6.3 | 2.1 | 2.0 | 2.1 | 1.4 | −1.9 | −1.2 | ||||||||||
GLYCOGEN | 2.0 | −1.9 | 1.5 | 7.2 | 1.0 | 1.0 | 8.8 | −1.0 | |||||||||||||||
ICDHACTIVITY | −1.2 | −1.5 | 1.4 | −1.4 | 5.4 | −1.8 | −6.9 | −1.8 | 1.4 | −1.0 | −1.4 | ||||||||||||
RCL4 | −1.1 | 1.4 | 2.3 | 1.3 | −4.9 | −4.3 | −5.1 | −1.5 | −3.0 | −1.5 | −2.5 | −3.4 | 1.6 | 2.3 | |||||||||
RCL3 | −2.1 | 2.0 | 2.2 | −4.0 | −5.5 | −4.6 | −2.5 | −3.7 | −2.3 | −2.2 | −3.1 | 2.0 | 2.5 | ||||||||||
RCL2 | −1.4 | 1.6 | 2.8 | −3.7 | −5.3 | −4.2 | −2.9 | −3.7 | −2.7 | −2.5 | −3.5 | −1.5 | 1.3 | 1.2 | 1.7 | ||||||||
RCL1 | 1.2 | 1.8 | −3.8 | −2.3 | −3.8 | −1.6 | −2.7 | −1.1 | 3.7 | 1.1 | 1.9 | 1.9 | 1.3 | 1.2 | |||||||||
RCb4 | 1.2 | −1.3 | −2.6 | 1.1 | 2.9 | 1.6 | 1.6 | −1.1 | |||||||||||||||
RCb3 | −1.7 | −2.0 | 1.7 | 1.0 | 1.5 | 1.2 | 1.8 | −2.8 | |||||||||||||||
RCb2 | −2.8 | −1.2 | 1.1 | −1.1 | 2.5 | 1.5 | 2.0 | 2.6 | 2.2 | ||||||||||||||
RCb1 | −1.7 | −2.6 | −2.0 | −1.8 | 5.0 | 1.9 | 3.6 | 3.2 | 1.4 | 1.3 | |||||||||||||
RCa4 | −1.6 | −3.3 | −1.6 | 4.1 | 3.9 | 2.1 | 1.3 | 1.4 | 7.4 | 4.1 | 1.5 | 2.1 | 2.4 | −1.5 | −1.1 | ||||||||
RCa3 | 1.1 | −2.7 | −1.1 | −3.9 | 1.2 | −1.7 | 2.0 | 3.7 | 5.6 | 2.6 | 2.0 | 7.5 | 4.7 | 1.6 | 1.6 | ||||||||
RCa2 | 1.2 | −2.4 | −1.7 | −4.1 | −1.3 | −1.6 | 3.6 | 3.2 | 5.3 | 2.3 | 1.6 | 7.2 | 6.0 | 1.4 | 1.5 | 1.3 | −1.1 | ||||||
RCa1 | −1.1 | −3.3 | −4.1 | −1.8 | 2.0 | 6.7 | 2.8 | 3.2 | 2.0 | 1.5 | 6.6 | 3.0 | 1.4 | −2.6 | |||||||||
CFb | −1.2 | −3.1 | 1.3 | −2.9 | 1.3 | −1.2 | 2.4 | 2.9 | 3.1 | ||||||||||||||
CFa | −1.6 | −3.9 | −2.4 | 6.9 | 3.9 | −1.0 | 3.4 | 4.3 | −1.4 | −1.2 | 1.9 | ||||||||||||
CFL | −1.2 | 1.0 | 1.3 | 1.3 | −5.9 | −2.4 | −6.1 | −3.7 | −2.3 | 1.7 | 2.5 | −1.1 | |||||||||||
PH24LL | 2.5 | 3.0 | −2.1 | −11.1 | −2.5 | −1.1 | −4.9 | −3.1 | −1.9 | 1.6 | |||||||||||||
PH24ST | −1.4 | −2.0 | −9.0 | −1.1 | 1.3 | −5.6 | −1.2 | −1.1 | −2.5 | ||||||||||||||
IRON | −2.8 | −1.5 | 1.4 | 5.2 | 6.2 | 3.7 | 1.4 | 1.5 | −1.9 | −1.3 | 1.1 | 1.2 | −2.7 | −3.5 | |||||||||
ZINC | 1.3 | −2.3 | −3.7 | −2.3 | 1.1 | −1.7 | −1.9 | ||||||||||||||||
EPADPADHA | 1.1 | −1.8 | 1.1 | −1.3 | 2.5 | 3.3 | −1.1 | −1.2 | −7.6 | −2.2 | 3.6 | −1.3 | 1.3 | ||||||||||
EPADHA | 1.0 | 1.2 | 1.9 | 4.3 | 1.5 | −1.3 | −7.5 | −2.1 | 2.6 | 1.6 | 1.9 | −1.2 | −1.8 | ||||||||||
FA_C22_6n3 | 2.5 | 1.1 | −1.4 | 2.8 | 1.0 | −1.8 | 2.4 | 3.6 | −1.3 | −1.3 | −6.8 | −1.0 | 1.5 | 2.6 | 6.8 | −1.6 | |||||||
FA_C22_5n3 | −1.5 | 2.8 | 1.0 | −1.4 | −1.1 | 1.0 | −1.3 | −5.8 | 3.5 | −2.7 | |||||||||||||
FA_C20_5n3 | 1.1 | 2.4 | 4.1 | −1.6 | 2.2 | −1.1 | −8.2 | 3.3 | 2.4 | ||||||||||||||
FA_C20_4n6 | 2.0 | 1.3 | 1.5 | 1.3 | −1.4 | 1.9 | 5.4 | −2.3 | 1.2 | 1.1 | −4.6 | −2.9 | −1.6 | 3.1 | |||||||||
FA_C20_3n6 | 2.1 | −1.4 | −1.2 | 2.6 | −1.2 | 2.2 | 2.8 | −2.0 | 2.1 | −5.7 | 2.4 | 8.2 | 1.3 | ||||||||||
FA_C18_2n6 | 2.7 | 3.7 | −2.0 | −6.1 | −1.8 | −2.2 | |||||||||||||||||
FA_C18_0 | −1.3 | 2.3 | 2.5 | −2.5 | −1.6 | −1.8 | −1.0 | −2.1 | −3.0 | −2.7 | 5.5 | 1.4 | 1.2 | 1.2 | |||||||||
FA_C16_0 | −1.8 | 3.6 | 4.9 | 6.0 | −1.6 | −1.1 | −1.3 | −1.6 | 1.2 | −2.0 | 1.2 | −1.0 | −1.1 | ||||||||||
FA_C14_0 | −2.7 | −2.7 | 4.9 | 8.4 | 3.7 | −2.9 | −1.2 | ||||||||||||||||
FA_C12_0 | −1.7 | 1.0 | −3.6 | −4.5 | 2.2 | 3.3 | 3.0 | −3.3 | −1.7 | 2.9 | 2.3 | −1.9 | |||||||||||
FA_C10_0 | 1.5 | −3.3 | 7.2 | 3.8 | 3.0 | −2.1 | −3.0 | −1.2 | −1.1 | 1.3 | 1.2 | 2.4 | −2.0 |