From: Detailed phenotyping identifies genes with pleiotropic effects on body composition
Group | Lead SNP | OAR | POS | Gene code | Gene name | Comments |
---|---|---|---|---|---|---|
Group1 | 1st | 16 | 31882270 | GHR | Growth hormone receptor precursor | Lead SNP |
Group1 | 1st | 8 | 73201627 | UST | uronyl-2-sulfotransferase | Linear Index SNP |
Group1 | 2nd | 14 | 34761382 | LCAT | lecithin-cholesterol acyltransferase | Lead SNP |
Group1 | 3rd | 11 | 26445930 | SLC16A13 (TP53 a) | Solute carrier family 16 member | Lead SNP |
Group1 | 3rd | 13 | 700413 | PLCB1 | Phosphoinositide phospholipase C | Linear Index SNP |
Group1 | 3rd | 5 | 28332019 | SNX24 | Sorting nexin-24 | Linear Index SNP |
Group1 | 3rd | 6 | 40133729 | PACRGL | PARK2 Co-Regulated-Like | Linear Index SNP |
Group1 | 3rd | 6 | 44672729 | PI4K2B | phosphatidylinositol 4-kinase type 2 beta | Linear Index SNP |
Group1 | 4Â th | 6 | 43309694 | PPARGC1A | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha | Linear Index SNP |
Group1 | 4Â th | 11 | 26415211 | ALOX12 | 12-lipoxygenase Fragment | Linear Index SNP |
Group1 | 4Â th | 11 | 28366019 | STX8 | Syntaxin 8 | Linear Index SNP |
Group1 | 4Â th | 1 | 171579973 | MYH15 | myosin, heavy chain 15 | Linear Index SNP |
Group1 | 4Â th | 6 | 13255764 | ALPK1 | alpha-kinase 1 | Linear Index SNP |
Group1 | 4Â th | 6 | 19164907 | TBCK | TBC1 domain containing kinase | Linear Index SNP |
Group1 | 4Â th | 6 | 23695577 | PPP3CA | protein phosphatase 3, Catalytic Subunit, Alpha Isozyme | Linear Index SNP |
Group1 | 4Â th | 6 | 26074029 | RAP1GDS1 | Rap1 GTPase-GDP dissociation stimulator 1 | Linear Index SNP |
Group1 | 4Â th | 6 | 29441012 | BMPR1B | bone morphogenetic protein receptor, type IB | Linear Index SNP |
Group1 | 4Â th | 6 | 36811936 | MEPE | Matrix Extracellular Phosphoglycoprotein | Linear Index SNP |
Group1 | 4Â th | 6 | 37237578 | NCAPG | non-SMC condensin I complex, subunit G | Linear Index SNP |
Group1 | 4Â th | 6 | 37530647 | LCORL | Ligand Dependent Nuclear Receptor Corepressor-Like | Lead SNP |
Group1 | 4Â th | 6 | 55607047 | ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 | Linear Index SNP |
Group1 | 4Â t | 6 | 67191744 | FRYL | FRY-like | Linear Index SNP |
Group1 | 4th | 9 | 36164331 | PLAG1 | pleiomorphic adenoma gene 1 | Linear Index SNP |
Group2 | 5th | 26 | 13991962 | ACSL1 | acyl-CoA synthetase long-chain family member 1 | Lead SNP |
Group2 | 6th | 11 | 13223903 | ACACA | acetyl-CoA carboxylase alpha | Linear Index SNP |
Group2 | 6th | 11 | 13272203 | Â | Â | Lead SNP |
Group2 | 6th | 11 | 13472077 | SYNRG | synergin, gamma | Linear Index SNP |
Group2 | 7th | 11 | 49936709 | FASN | Fatty acid synthase Fragment | Lead SNP |
Group2 | 7th | 13 | 71732382 | SGK2 | serum/glucocorticoid regulated kinase 2 | Linear Index SNP |
Group2 | 7th | 24 | 33535204 | MLXIPL | MLX interacting protein-like | Linear Index SNP |
Group2 | 7th | 5 | 4503837 | ISYNA1 | Inositol-3-phosphate synthase 1 | Linear Index SNP |
Group2 | 8th | 6 | 15245427 | SNORA70 | small nucleolar RNA, H/ACA box 70 | Lead SNP |
Group2 | 8th | 6 | 15303638 | ELOVL6 | ELOVL fatty acid elongase 6 | Linear Index SNP |
Group2 | 8th | 6 | 97914579 | AGPAT9 | 1-acylglycerol-3-phosphate O-acyltransferase 9 | Linear Index SNP |
Group3 | 9th | 19 | 57102703 | MRPS25 | 28S ribosomal protein S25, mitochondrial | Lead SNP |
Group3 | 9th | 3 | 178861487 | MB | Myoglobin | Linear Index SNP |
Group3 | 10th | 1 | 31018467 | PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit | Linear Index SNP |
Group3 | 10th | 2 | 212089089 | ERBB4 | v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4 | Linear Index SNP |
Group3 | 10th | 2 | 219569259 | PLCD4 | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-4 | Lead SNP |
Group3 | 10th | 2 | 219741728 | CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 | Linear Index SNP |
Group3 | 11th | 23 | 5077077 | NETO1 | neuropilin (NRP) and tolloid (TLL)-like 1 | Linear Index SNP |
Group3 | 11th | 3 | 178935942 | APOL6 | apolipoprotein L, 6 | Lead SNP |
Group3 | 12th | 11 | 19757132 | PROCA1 | Protein PROCA1 | Linear Index SNP |
Group3 | 12th | 21 | 42744428 | CAPN1 | Calpain-1 catalytic subunit | Linear Index SNP |
Group3 | 12th | 3 | 193152752 | ABCC9 | ATP-binding cassette, sub-family C (CFTR/MRP), member 9 | Linear Index SNP |
Group3 | 12th | 5 | 93437720 | CAST | Calpastatin | Lead SNP |
Group3 | 13th | 18 | 63919438 | WARS | Tryptophanyl-tRNA synthetase, cytoplasmic | Linear Index SNP |
Group3 | 13th | 18 | 64095685 | BEGAIN | brain-enriched guanylate kinase-associated | Linear Index SNP |
Group3 | 13th | 18 | 64349803 | DLK1 | delta-like 1 homolog | Linear Index SNP |
Group3 | 13th | 18 | 64452243 | MEG3_2 | maternally expressed 3 | Linear Index SNP |
Group3 | 13th | 18 | 64496663 | MEG8_2 | maternally expressed 8 | Lead SNP |
Group3 | 13th | 18 | 66755669 | MARK3 | MAP/microtubule affinity-regulating kinase 3 | Linear Index SNP |
Group4 | 14th | 8 | 25030751 | (LAMA4) | laminin, alpha 4 | Lead SNP |
Group4 | 15th | 18 | 6026853 | MEF2A | Myocyte-specific enhancer factor 2A | Linear Index SNP |
Group4 | 15th | 1 | 373512 | FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 | Linear Index SNP |
Group4 | 15th | 22 | 20348430 | PKD2L1 (SCD b) | polycystic kidney disease 2-like 1 | Lead SNP |
Group4 | 16th | 12 | 49339905 | B3GALT6 | UDP-Gal-betaGal beta 1,3-galactosyltransferase polypeptide 6 | Linear Index SNP |
Group4 | 16th | 12 | 49639530 | SAMD11 | sterile alpha motif domain containing 11 | Lead SNP |
Group4 | 16th | 17 | 63396022 | MYO1H | myosin IH | Linear Index SNP |
Group4 | 16th | 12 | 49270130 | GLTPD1 | glycolipid transfer protein domain containing 1 | Linear Index SNP |
Group5 | 17th | 14 | 54580893 | GYS1 | Glycogen synthase, muscle | Lead SNP |
Group5 | 17th | 4 | 54562436 | PPP1R3A | protein phosphatase 1, regulatory (inhibitor) subunit 3A | Linear Index SNP |
Group5 | 18th | 3 | 218656000 | PNPLA3 | patatin-like phospholipase domain containing 3 | Lead SNP |
Group5 | 19th | 21 | 39759701 | FADS2 | Fatty acid desaturase 2 | Lead SNP |
Group5 | 20th | 19 | 30808702 | 5S_rRNA | RNA, 5S ribosomal | Lead SNP |
Group5 | 21th | 20 | 44129579 | SMIM13 | small integral membrane protein 13 | Lead SNP |
Group5 | 21th | 20 | 44237093 | ELOVL2 | ELOVL fatty acid elongase 2 | Linear Index SNP |
Group5 | 22th | 21 | 14965281 | Â | Â | Lead SNP |
Group5 | 23th | 15 | 47513135 | U1 | RNA, variant U1 | Lead SNP |
Group5 | 23th | 25 | 29372500 | USP54 | ubiquitin specific peptidase 54 | Linear Index SNP |