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Table 3 Numbers and vectors of DNA methylation and gene expression changes in murine hearts after birth

From: Changes in gene methylation patterns in neonatal murine hearts: Implications for the regenerative potential

   Number of DMRs and transcripts pairs
  Relationship Distal Proximal Intragenic Total
d1-d7 MeDIP↑ Expression↑ 89 43 28 160
  MeDIP↑ Expression↓ 55 17 11 83
  MeDIP↓ Expression↑ 6 6 6 18
  MeDIP↓ Expression↓ 6 5 1 12
d1-w2 MeDIP↑ Expression↑ 21 17 19 57
  MeDIP↑ Expression↓ 14 21 9 44
  MeDIP↓ Expression↑ 146 30 50 226
  MeDIP↓ Expression↓ 27 119 44 190
d1-w8 MeDIP↑ Expression↑ 121 23 23 167
  MeDIP↑ Expression↓ 143 43 13 199
  MeDIP↓ Expression↑ 245 311 118 674
  MeDIP↓ Expression↓ 135 178 97 410
  1. The summary includes the numbers of DMRs paired with corresponding transcripts changing their expression levels by at least a 1.5-fold. The relationships are visualized in Figs. 6, 7, 8
  2. MeDIP↑/MeDIP↓ - DNA methylation gain/loss
  3. Expression↑/Expression↓ - increase/decrease