Table 6 Top 10 transcripts in both directions for the RIF2 analysis. The RIF2 analysis was performed on blood RNA DE genes contrasting AB minus AA animals. The transcript ID, gene symbol and gene name is shown, together with the RIF2 calculated z-score. The positive RIF2 scores are > 2, the negative RIF2 scores are < -2, and thus all genes presented here are highly significant, which indicates a large difference between WUR genotypes in linkages to these hub genes
Transcript_id | Gene symbol | Gene | RIF2 z-score |
|---|---|---|---|
ENSSSCT00000005054 | - | uncharacterized | -12.312 |
ENSSSCT00000002033 | IQGAP1 | IQ motif containing GTPase activating protein 1 | -10.874 |
ENSSSCT00000007586 | CCBL2 | cysteine conjugate-beta lyase 2 | -10.365 |
ENSSSCT00000004284 | EPS15 | epidermal growth factor receptor pathway substrate 15 | -8.242 |
ENSSSCT00000002542 | FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -7.621 |
ENSSSCT00000005334 | UBE3A | ubiquitin protein ligase E3A | -7.528 |
ENSSSCT00000007421 | CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -7.337 |
ENSSSCT00000007964 | DYNLRB1 | dynein, light chain, roadblock-type 1 | -7.336 |
ENSSSCT00000010053 | RG9MTD2 | tRNA methyltransferase 10 homolog A | -7.285 |
ENSSSCT00000001175 | CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -6.995 |
ENSSSCT00000002288 | - | 40S ribosomal protein S3a | 7.188 |
ENSSSCT00000004971 | ATP5A1 | ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1 | 7.207 |
ENSSSCT00000009172 | CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 7.218 |
ENSSSCT00000006787 | TRAM1 | translocation associated membrane protein 1 | 7.360 |
ENSSSCT00000004039 | SF3A3 | splicing factor 3a, subunit 3, 60Â kDa | 7.966 |
ENSSSCT00000000103 | TOMM22 | translocase of outer mitochondrial membrane 20 homolog | 8.628 |
ENSSSCT00000005108 | LEO1 | Paf1/RNA polymerase II complex component | 8.708 |
ENSSSCT00000002242 | PSME2 | proteasome activator subunit 2 (PA28 beta) | 9.040 |
ENSSSCT00000002808 | RPS21 | ribosomal protein S21 | 11.614 |
ENSSSCT00000004960 | EF1ALPHA | eukaryotic translation elongation factor 1 alpha 1 | 11.644 |