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Fig. 2 | BMC Genomics

Fig. 2

From: The orientation of transcription factor binding site motifs in gene promoter regions: does it matter?

Fig. 2

Visualization of the results statistics reported in Table 2 and (Additional file 2: Table S1). Percentages of motifs passing through the various filter criteria (C, D1, D2, and E) as explained in table legend 2 are plotted for the different upstream sequence intervals considered in this study and true motif sets (293 upstream elements, 10 core promoter elements). Results statistics are compared to sets of randomized motifs generated by either assuming base composition as observed in the respective upstream sequence interval (R1) or as observed in true motifs (R2) (see Methods, and Additional file 2: Table S1). Significant differences are annotated as “+”/”#” if percentages obtained for true motifs differed from R1/R2-randomized sets, respectively, with triple-symbols indicating p < 0.001, double-symbols p < 0.01, and single-symbols p < 0.05 after correcting for multiple testing

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