Fig. 3

K-means clustering of the Z-score values of each differentially expressed CDS and ncRNA genes in the five different growth conditions, and Clusters of Orthologous Group (COG) affiliation of the CDS of each K-means cluster. a Heatmap depicting the K-means clustering of the 2 052 differentially expressed CDS in 10 clusters with column hierarchical clustering. The average Z-scores of the 10 clusters was calculated for each condition, and the 13 clusters presenting an average Z-score value > 1 or < −1 were framed. Blue and red clusters gathered genes under- or overexpressed compared to the mean, respectively (b) K-means clustering of the 19 differentially expressed ncRNA genes in 5 clusters. Locus tag of each ncRNA gene, and its respective annotation in parentheses, are indicated. Blue and red clusters gathered genes under- or overexpressed compared to the mean, respectively (c) Clusters of Orthologous Group (COG) affiliation of the CDS of each K-means cluster. Only COG categories containing more than 10 % of the CDS of one cluster are presented. The circle size is proportional to the percentage of CDS (indicated by numbers) affiliated to a COG category for one given cluster group. Percentages in red correspond to the major part of each cluster. COG categories not presented are grouped in the “other COG” category. An exhaustive view of the CDS composition of each cluster and their COG affiliation is provided in Additional file 2: Table S1 and in Additional file 6: Figure S3