Fig. 5
Expression profile of component genes of the monodictyphenone and orsellinic acid clusters under ionic liquid stimuli. Representation of the gene clusters involved in the biosynthesis of monodictyphenone (a) and orsellinic acid (b) in Aspergillus nidulans. Essential and non-essential genes are shown in black and grey (arrows), respectively (adapted from [4, 37]). Below each gene the measured fold-change (FC) in either choline or 1-ethyl-3-methylimidazolium chloride ([C2mim]Cl) supplemented media are depicted (microarray data) and, if statistically significant (|FC| ≥ 1.5 and p-value ≤ 0.05), indicated with an asterisk (*)