Fig. 1
5hmC is enriched in the gene bodies of active genes while 5mC is depleted at the 5’ regions of active genes. (a and b). Pie chart depicts accumulation of 5hmC or 5mC DIP-Seq signal in the indicated genomic regions. Data that matched multiple categories was matched to the closest annotation. (c and d). Heatmaps depict DIP-Seq sequence density (500 bp bins) at RefSeq genes rank-ordered by levels of gene expression (RNA-Seq data from other studies). The color ramp shows min-max DIP/ChIP signal density normalized to the 80th quantile. The black bar illustrates the transcribed region with the 5’ end on the left