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Table 2 Joint linkage-association analysis of serum uric acid (mg/dl) on chromosome 3

From: GWAS and transcriptional analysis prioritize ITPR1 and CNTN4 for a serum uric acid 3p26 QTL in Mexican Americans

SNPa Gene Coordinates NCBI36 (bp) JLAb (p-value) MGAc (p-value) Minor allele/frequency
rs17040820 ITPR1 d 4531694 1.3 × 10−10 9.4 × 10−10 T/0.003
rs7640752 Intergenic 114123136 8.6 × 10−10 1.9 × 10−10 A/0.005
rs11916691 DCP1A e 53350244 9.2 × 10−10 2.0 × 10−10 A/0.005
rs1395388 TGM4 f 44923678 1.8 × 10−8 4.2 × 10−9 G/0.05
rs449361 ARHGEF26 g 155405100 2.8 × 10−8 6.6 × 10−9 T/0.05
rs1014805 CNTN4 h 2310471 7.7 × 10−8 9.1 × 10−4 C/0.33
rs2535632 ITIH4 i 52839315 1.8 × 10−7 4.3 × 10−8 T/0.03
rs9854606 CNTN4 2380442 1.9 × 10−7 2.9 × 10−3 T/0.004
rs1685456 CNTN4 2321860 2.1 × 10−7 1.8 × 10−3 C/0.43
rs1685447 CNTN4 2313137 2.1 × 10−7 3.4 × 10−3 A/0.27
rs1178487 CNTN4 2315743 2.2 × 10−7 3.0 × 10−3 T/0.41
rs17013501 CNTN4 2396201 2.5 × 10−7 5.0 × 10−3 T/0.22
rs6808240 CNTN4 2397321 3.3 × 10−7 8.8 × 10−3 C/0.27
rs1178492 CNTN4 2318040 3.7 × 10−7 7.7 × 10−3 T/0.27
rs1502582 CNTN4 2326831 3.7 × 10−7 6.7 × 10−3 T/0.24
rs1720201 CNTN4 2313231 4.4 × 10−7 1.1 × 10−2 G/0.27
  1. aSNP: Single Nucleotide Polymorphism; bJLA: Joint Linkage Association Analysis; cMGA: Measured Genotype Analysis; d ITPR1: inositol 1,4,5-trisphosphate receptor, type 1; e DCP1A: decapping mRNA 1A; f TGM4: transglutaminase 4; g ARHGEF26: Rho guanine nucleotide exchange factor (GEF) 26; h CNTN4: Contactin 4; i ITIH4: inter-alpha-trypsin inhibitor heavy chain family, member 4