Table 4 Genome-wide association of ITPR1 transcript levels
SNPa | Geneb | Chr | Coordinates NCBI36 (bp) | MGAc (p-value) | JLAd (p-value) | Effect sizee (%) | Minor allele | MAFf |
|---|---|---|---|---|---|---|---|---|
rs877850 | Intergenic | 1 | 216328255 | 2.35 × 10−7 | 9.05 × 10−7 | 2.61 | G | 0.12 |
rs9311419 | ITPR1 | 3 | 4855671 | 9.12 × 10−7 | 3.37 × 10−6 | 2.58 | T | 0.14 |
rs4685832 | ITPR1 | 3 | 4859817 | 1.19 × 10−6 | 4.37 × 10−6 | 2.50 | G | 0.16 |
rs12581731 | SCN8A | 12 | 50311004 | 2.54 × 10−6 | 8.89 × 10−6 | 1.97 | A | 0.12 |
rs3805034 | ITPR1 | 3 | 4855266 | 4.22 × 10−6 | 1.48 × 10−6 | 2.31 | A | 0.12 |
rs3805035 | ITPR1 | 3 | 4855300 | 4.94 × 10−6 | 1.72 × 10−6 | 2.30 | T | 0.13 |
rs10886848 | Intergenic | 10 | 122831260 | 1.41 × 10−5 | 3.44 × 10−5 | 1.73 | A | 0.46 |
rs10170245 | LOC105373893 | 2 | 220897407 | 1.61 × 10−5 | 5.36 × 10−5 | 1.67 | A | 0.09 |
rs4561600 | Intergenic | 2 | 142915296 | 1.71 × 10−5 | 5.70 × 10−5 | 1.58 | G | 0.17 |
rs4553758 | Intergenic | 2 | 142914017 | 1.83 × 10−5 | 6.07 × 10−5 | 1.50 | A | 0.21 |