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Table 3 Validation of 17 high-impact SNPs in 337 fertile stallions

From: Screening of whole genome sequences identified high-impact variants for stallion fertility

  

HWE

Polymorphism

Candidate gene

HET

X 2

DF

P-HWE

g.26775767G>C

NEURL

0.116

22.094

1

<0.0001

g.77472655G>C

KDR

0.228

0.324

1

0.569

g.74610774C>T

CFTR

0.004

0.001

1

0.976

g.56937215C>T

OVGP1

0.111

0.810

1

0.368

g.45985131A>G

FBXO43

0.032

0.082

1

0.775

g.82699661C>T

TSSK6

0.068

0.380

1

0.538

g.7083659A>T

SLC9A3R1

0.398

0.476

1

0.490

g.40694339G>A

PKD1

0.013

0.013

1

0.911

g.6704968C>T

GHRL

0.019

18.572

1

<0.001

g.19034281C>T

FOXP1

0.104

0.959

1

0.327

g.32635273T>C

BTNL2

0.168

120.250

1

<0.0001

g.35255390T>C

TCP11

0.022

0.040

1

0.842

g.4323852G>A

SPATA31E1

0.009

0.007

1

0.933

g.37453246G>C

NOTCH1

0.023

0.040

1

0.841

g.37455302G>A

NOTCH1

0.226

0.272

1

0.602

g.79813487A>T

ENSECAG00000020135

0

0

0

–

g.25184403G>C

ENSECAG00000021286

0

0

0

–

  1. For each polymorphism, corresponding candidate gene, heterozygosity (HET), test for Hardy Weinberg equilibrium (HWE) with the respective chi square (X 2) statistic, degrees of freedom (DF) and P-value (P-HWE) are given