Fig. 4

Analysis by qPCR of the expression of two genes encoding proteins involved in translation and transcription: Histone 2B (a) and 26S proteasome regulatory complex, subunit RPN10/PSMD4 (b). The data represent the average fold change of 3 independent biological replicates ± SEM. Normalization was done using the pp2ase gene as housekeeping gene. Fold change was calculated compared to the value obtained for the dark control sample. The non-parametric Mann-Whitney U test (Statistica 12) was used to determine the significance of the results