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Fig. 8 | BMC Genomics

Fig. 8

From: Lactation undernutrition leads to multigenerational molecular programming of hypothalamic gene networks controlling reproduction

Fig. 8

Molecular changes in the hypothalami of 21-day old female F2 progeny. a Expression pattern of Kisspeptin-signaling related genes. Genes showing increased b and decreased c expression in hypothalami of F1 undernourished neonates were tested in F2 females. Expression levels are presented relative to Ppib expression (arbitrary units (AU)). Means (blue line) with different superscripts differ significantly (statistical significance was calculated by One-way ANOVA; n = 12/breeding protocol (CxC, CxL, LxC, LxL)). C – CON (F1 control progeny), L – LUN (F1 progeny undernourished during lactation)

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