Fig. 2

Global ATF3-binding profile under the basal condition. a A pie chart showing distribution of ATF3 binding sites relative to annotated genes. b 600 annotated genes with top peak scores were used for DAVID GO analysis. GO biological process (BP) terms and KEGG pathway terms are shown. c Top motifs identified in the ATF3 binding sites. d Schematic showing relative abundance and overlaps of the three known ATF3 binding motifs. The numbers are peak numbers. e The binding of ATF3 to the ATF/CRE motif appeared to be stronger than the AP-1 motif. Student t-test. f A table showing top motifs after combining motifs with same/similar sequences. g Venn diagram showing overlaps of CTCF, GATA3, and TEAD motifs with the ATF3 motif