Fig. 12
From: High-specificity detection of rare alleles with Paired-End Low Error Sequencing (PELE-Seq)
A SNP near srh-265 at 21.5 % in the lab-adapted and 0 % in the wild C. remanei. When a minimum read depth of 800× OPE was used to detect putative de novo alleles, a C > A transversion was found that increased from 0/862 reads in the wild population to 153/811 reads (21.5 %) in the lab-adapted population. This SNP is upstream of a gene predicted by UCSC to be homologous to the C. elegans gene srh-265, which codes for a serpentine receptor, of class H. The top panel shows 500 sequencing reads from the ancestral (wild) population; the bottom panel shows 500 sequencing reads from the lab-adapted population. The non-reference SNP at position 90,148,415 of the caeRem3 genome is visible in red