Fig. 13
From: High-specificity detection of rare alleles with Paired-End Low Error Sequencing (PELE-Seq)
Putative de novo SNPs are more numerous than SNPs lost during lab-adaptation of C. remanei. With PELE-Seq we identified 91 putative de novo mutations that are found only in the lab-adapted C. remanei population (red), and 19 SNPs found only in the wild population (blue), using a minimum read depth of 900× OPE. Each vertical line represents a single SNP and the height of the line is proportional to the allele frequency. The SNPs present only in the lab-adapted population occur more frequently (91 vs. 19 SNPs) and with higher allele frequencies (max 16 % vs 6 %) than the SNPs present only in the wild population