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Table 1 Summary of TIGER results in non-human primate species

From: Next-generation sequencing-based detection of germline L1-mediated transductions

Species Sample Physical coverage (X) Non-reference L1 insertions TIGER transductions L1 transduction rate (%)* PCR validated transductions
Macaque AG06249 26.0 449 29 5.5 ± 1.2** 14/16
AG06252 29.2 620 28   
AG07098 21.7 424 26   
AG07109 23.7 473 28   
AG07110 18.6 635 28   
Orangutan AG06105 19.2 663 52 8.8 ± 1.4** 24/28
AG06209 24.2 803 81   
GM04272 24.0 649 62   
PR00054 23.3 775 70   
PR01110 17.2 633 47   
Chimpanzee PR00226 32.2 214 4 2.5 ± 1.1** 5/7
PR00738 32.9 246 7   
PR00818 28.2 223 4   
PR01106 19.8 148 3   
PR01171 18.8 132 5   
  1. For comparison to NA12878 see Additional file 1: Table S5
  2. *Determined based on ratio between TIGER transductions and L1 insertions. 95 % confidence intervals were calculated using one sample t-test
  3. **Significantly different based on Wald test of predicted-transduction rates: chimpanzee-macaque: P = 0.000073; chimpanzee-orangutan: P = 0.000037; macaque-orangutan: P = 0.0003