Skip to main content

Table 1 P-values for the stop codon frequencies in four Gene Expression Barcode categories

From: Selective forces and mutational biases drive stop codon usage in the human genome: a comparison with sense codon usage

Gene Expression Barcode category p(x ≤ n.TAA) p(x ≥ n.TAA) p(x ≤ n.TAG) p(x ≥ n.TAG) p(x ≤ n.TGA) p(x ≥ n.TGA)
Pr = 0 0.2063 0.8067 0.8275 0.1844 0.4802 0.5354
0 < Pr ≤ 0.5 0.2502 0.7571 0.1865 0.8199 0.9150 0.0881
0.5 < Pr < 1 0.9994 7.03E-04 0.5168 0.5061 1.55E-03 0.9987
Pr = 1 1.0000 1.07E-08 5.00E-02 0.9684 4.61E-05 1.0000
  1. Genes were clustered into four categories by proportion of cell types in which a gene was estimated as expressed (Pr). P-values were computed on the basis of Poisson binomial cumulative distribution. The probability p of codon occurrence in each gene was set equal to the codon fraction expected at the GC-content of its CDS