Fig. 4
From: Improving microRNA target prediction with gene expression profiles
Performance comparison using high-throughput sequencing data of zebrafish embryos. Experimental profiles compared wild type and dicer mutant embryos at 6 h postfertilization, when a clear difference of miR-430 targets is observed [2]. We compared a) TargetExpress predictions to TargetScan restricted to targets with expression higher than percentiles: b) 0, c) 25, d) 50 and e) 75. The Y-axis shows the Area Under the Curve metric (AUC), with 95 % confidence intervals. Green bars represent performance when using mRNA expression, blue bars ribosome profiling. Dashed lines indicate TargetExpress AUCs