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Fig. 3 | BMC Genomics

Fig. 3

From: Enhanced whole exome sequencing by higher DNA insert lengths

Fig. 3

Evenness between different insert groups and unmerged/merged sequences. Before (a) and after (b) normalisation of coverage to the fraction of respective target regions for unmerged sequences. The complete integral of normalised coverage to the target region is summing up to 1. c The evenness score computed from the area under the curve of unmerged (Fig. 3 b) and merged sequences between 0 and 1 normalised coverage. The closer the evenness score is to 1, the better the uniformity of base coverage. The impact of higher insert length was evident; merged inserts gained top evenness scores regardless of relating to the specific corresponding target region or to overlapping target regions

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