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Fig. 6 | BMC Genomics

Fig. 6

From: Genome-wide analysis of the transcriptional response to porcine reproductive and respiratory syndrome virus infection at the maternal/fetal interface and in the fetus

Fig. 6

Expression of genes that function in leukocyte activation in uninfected fetuses. Expression of differentially expressed genes from the UNINF v CON contrast in fetus that are annotated with the term ‘activation of leukocytes’ in Ingenuity Pathway Analysis (IPA). Gene color indicates strength and direction of expression change: red color represents upregulation of gene expression in UNINF group; green color represents downregulation of gene expression in UNINF group. Arrow color indicates whether the observed direction of expression for that gene and its potential effect on leukocyte activation is consistent with what would be expected based on experimental evidence curated in the Ingenuity Knowledge Base. An orange line indicates that the direction of expression of that gene is consistent with activation. A yellow line indicates that the direction of expression of that gene is consistent with inhibition. A grey line indicates no known relationship. The predominance of orange arrows reflects the fact that this function exhibited a tendency to be activated by biological function analysis in IPA (Z score of 1.967)

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