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Table 3 Summary of the KinMutRF and PON-BTK prediction results

From: KinMutRF: a random forest classifier of sequence variants in the human protein kinase superfamily

  Pathogenic Neutral
  Prediction Overlap Diff. Prediction Overlap Diff.
KinMutRF 1285 (85.9 %) 967   210 (14.1 %) 174  
PON-BTK 1003 (67.1 %)   36 492 (32.9 %)   318
  1. Prediction: indicates the total number of BTK variants predicted as pathogenic and neutral. Numbers in parenthesis represent the percentage from a maximum of 1495 possible nonsynonymous variants. Overlap: total number of BTK variants predicted as pathogenic and neutral by KinMutRF and PON-BTK. Diff.: total number of BTK variants with different predictions by KinMutRF and PON-BTK