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Fig. 5 | BMC Genomics

Fig. 5

From: Large scale analysis of protein stability in OMIM disease related human protein variants

Fig. 5

Relation between the per-protein fraction of solvent accessible variations and the corresponding number of the wild-type partners of interactions in the human interactome. The box-plot reports the median and the lower and upper quartiles of the number of interactions present in IntAct as a function of the fraction of solvent accessible variations. The dashed blue line connects the average values. Data refers to 170 proteins with 4037 variations of our data set. Proteins with less than 5 disease-related variations or without interactomic data reported in IntAct are excluded

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