Table 2 Relation between thermodynamic properties and structural properties in proteins with biologically functional monomeric assembly

|ΔΔG| ≤ 1

562 (23.4 %)^a 398

756 (31.4 %)^a 39

|ΔΔG| > 1

176 (7.3 %)^a 120

907 (37.8 %)^a 36

Polymorphic variant

|ΔΔG| ≤ 1

194 (59.0 %)^a 110

72 (21.9 %)^a 3

|ΔΔG| > 1

22 (6.7 %)^a 10

41 (12.5 %)^a 0