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Fig. 1 | BMC Genomics

Fig. 1

From: Negative selection maintains transcription factor binding motifs in human cancer

Fig. 1

Procedure used to evaluate affinity change events and estimate significance of difference between observed and expected frequencies. Top panel: prediction of binding sites in cancer and control data and evaluation of affinity change events. Bottom panel: binding sites predictions and affinity change events of AP-2 motifs; an example of 2 × 2 contingency table used to compute Fisher’s exact test P-value

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