Fig. 5
From: Genome-wide alteration of 5-hydroxymenthylcytosine in a mouse model of Alzheimer’s disease
Identification and characterization of DhMRs in AD mouse model. a A representative IGV image shows the reduction of overall 5hmC in aged DTg mice compared to WT mice and adult DTg mice. b-c Representative IGV images show the decrease of 5hmC in some genomic regions of Ank1 and Cdh23. d 5hmC highly enriched in the gene body of APP gene in adult and aged DTg mice compared to WT mice. MACS software default statistic test, p-value cutoff: 1X10−5
