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Fig. 3 | BMC Genomics

Fig. 3

From: A de novo transcriptome analysis shows that modulation of the JAK-STAT signaling pathway by salmonid alphavirus subtype 3 favors virus replication in macrophage/dendritic-like TO-cells

Fig. 3

Schematic presentation of the Jak/stat pathway genes induced by SAV-3 infection without type I IFN treatment (TO-VS-SAV3) and type I IFN treated cells (TO-VS-IFN/SAV3) infected with SAV3. Note each group is subdivided into type I and II receptors, Jak and tyrosine kinases, negative regulators and signal transducers. a shows that the TO-VS-SAV3 had more type I receptor than the TO-VS-IFN/SAV3 shown in b. Among the type II receptors, the IFNGR1 and IFNGR2 were only reported in the TO-VS-IFN/SAV3 and not in the TO-VS-SAV3 while among the Jaks, Tyk2 was only expressed in the TO-VS-SAV3 and not in TO-VS-IFN/SAV3. For the signal transducer, Stat5B was only expressed in the TO-VS-SAV3 and not in the TO-VS-IFN/SAV3 while Stat6 was only expressed in the TO-VS-IFN/SAV3 and not in the TO-VS-SAV3

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BMC Genomics

ISSN: 1471-2164

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