Transcriptome analysis of human brain tissue identifies reduced expression of complement complex C1Q Genes in Rett syndrome

Table 1 Genes differentially expressed in mouse and human Rett syndrome brain

Gene Symbol	FDR	Log2FC	Log2FC	Log2FC
Gene Symbol	FDR	Log2FC	Mecp2 null/WT	MECP2 Tg/WT
C1QA	0.002	−1.776	−0.278^a	0.196
CTSS	0.018	−1.407	−0.122^a	0.291^a
C1QC	0.030	−1.355	−0.318^a	0.195
C1QB	0.043	−1.337	−0.287^a	0.38^a
B3GNT5	0.019	−1.266	−0.351^a	0.137
NR4A3	0.003	−0.952	−0.313^a	0.122
GLRA3	0.041	−0.625	−0.288^a	0.411^a
AUTS2	0.027	0.572	0.274^a	−0.227^a
FSTL4	0.046	0.723	0.311^a	−0.117^a
ESRRG	0.001	0.960	0.226^a	−0.346^a
CD83	0.004	1.121	0.096	−0.336^a
VAV3	0.000	1.326	0.118^a	−0.313^a
FKBP5	0.015	1.885	0.087	−0.397^a

ISSN: 1471-2164