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Table 5 Variant types: acquired and selected variants in MCF-7 sub-lines

From: The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells

Consequence MCF-7 MCF-7 MCF-7 MCF-7 MCF-7
SUB-0.27nM SUB-1.2nM SUB-7.5nM SUB-45nM RES-65nM
3 prime UTR variant 26 6 2 2 29
5 prime UTR variant 6 6 1 2 21
NMD transcript variant 70 33 3 14 128
TF binding site variant 0 0 0 0 0
Downstream gene variant 169 85 29 38 236
Feature elongation 29 2 8 22 20
Feature truncation 63 38 7 18 75
Frameshift variant 0 1 0 0 0
Inframe insertion 0 0 0 0 0
Intron variant 618 228 70 136 656
Mature miRNA variant 0 0 0 0 0
Missense variant 44 55 0 12 85
Nc transcript variant 182 89 12 58 203
Non coding exon variant 45 36 3 13 75
Regulatory region variant 27 13 5 12 54
Splice acceptor variant 0 0 0 0 12
Splice region variant 12 5 1 6 17
Stop gained 0 4 0 0 10
Synonymous variant 35 24 3 5 68
Upstream gene variant 95 66 13 38 195
Total 1421 691 157 376 1884